[HTML][HTML] Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

…, S Kanbour, S Sarkar, GSF Monaco, DM Scholtens… - Nature medicine, 2023 - nature.com
Precision medicine is part of the logical evolution of contemporary evidence-based medicine
that seeks to reduce errors and optimize outcomes when making medical decisions and …

Genetics of gestational diabetes mellitus and maternal metabolism

WL Lowe, DM Scholtens, V Sandler, MG Hayes - Current diabetes reports, 2016 - Springer
Gestational diabetes mellitus (GDM) is defined as abnormal glucose tolerance with onset or
first recognition during pregnancy. Women with a history of GDM are at long-term risk for …

Genome-wide associations for birth weight and correlations with adult disease

…, J Tyrrell, AR Wood, H Yaghootkar, DM Scholtens… - Nature, 2016 - nature.com
Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in
observational studies is reproducibly associated with future risk of adult metabolic diseases …

Association of gestational diabetes with maternal disorders of glucose metabolism and childhood adiposity

WL Lowe, DM Scholtens, LP Lowe, A Kuang… - Jama, 2018 - jamanetwork.com
… Author Contributions: Drs Scholtens and Metzger had full access to all of the data in the
study and take responsibility for the … Lowe Jr and Scholtens contributed equally to this work. …

Hyperglycemia and adverse pregnancy outcome follow-up study (HAPO FUS): maternal gestational diabetes mellitus and childhood glucose metabolism

WL Lowe Jr, DM Scholtens, A Kuang, B Linder… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE Whether hyperglycemia in utero less than overt diabetes is associated with
altered childhood glucose metabolism is unknown. We examined associations of gestational …

Covid-19 and the politics of sustainable energy transitions

…, A Goldthau, J Jewell, I Overland, D Scholten… - Energy Research & …, 2020 - Elsevier
In this perspectives piece, an interdisciplinary team of social science researchers considers
the implications of Covid-19 for the politics of sustainable energy transitions. The emergency …

[HTML][HTML] Genetic evidence for causal relationships between maternal obesity-related traits and birth weight

…, JC Murray, B Hocher, AT Hattersley, DM Scholtens… - Jama, 2016 - jamanetwork.com
Importance Neonates born to overweight or obese women are larger and at higher risk of
birth complications. Many maternal obesity-related traits are observationally associated with …

[HTML][HTML] NFKBIA Deletion in Glioblastomas

M Bredel, DM Scholtens, AK Yadav… - … England Journal of …, 2011 - Mass Medical Soc
Background Amplification and activating mutations of the epidermal growth factor receptor (EGFR)
oncogene are molecular hallmarks of glioblastomas. We hypothesized that deletion of …

Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer

…, MF Mulcahy, KL Dennis, D Scholtens… - Science translational …, 2012 - science.org
The role of regulatory T cells (T regs ) in human colon cancer (CC) remains controversial:
high densities of tumor-infiltrating T regs can correlate with better or worse clinical outcomes …

Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): maternal glycemia and childhood glucose metabolism

DM Scholtens, A Kuang, LP Lowe, J Hamilton… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE This study examined associations of maternal glycemia during pregnancy with
childhood glucose outcomes in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO…