User profiles for D. Polygalov

Denis Polygalov

Technical Staff, Laboratory for Circuit and Behavioral Physiology, RIKEN Center for Brain …
Verified email at brain.riken.jp
Cited by 534

A hypothalamic novelty signal modulates hippocampal memory

…, R Boehringer, V Robert, ME Wintzer, D Polygalov… - Nature, 2020 - nature.com
d, Behavioural recording protocol; sequential exposure to a familiar context, a novel context
and … Axons targeting the hippocampus are shown in d and soma in the SuM are shown in e. …

[PDF][PDF] Chronic loss of CA2 transmission leads to hippocampal hyperexcitability

R Boehringer, D Polygalov, AJY Huang, SJ Middleton… - Neuron, 2017 - cell.com
d CA2 driven feedforward inhibition in CA3 is crucial for hippocampal E/I balance … (D)
Diagram of the extracellular recording configuration of the CA3-CA1 and CA3-CA3 measurements …

The hippocampal CA2 ensemble is sensitive to contextual change

ME Wintzer, R Boehringer, D Polygalov… - Journal of …, 2014 - Soc Neuroscience
… A–D, We performed double FISH with a probe for NR1 (green) and CACNG5 (red). A,
The 5× epifluorescent image of a coronal section of the dorsal hippocampus of the flNR1/flNR1 …

Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1

…, J Cognet, AJY Huang, R Boehringer, D Polygalov… - Elife, 2021 - elifesciences.org
The hippocampus is critical for memory formation. The hypothalamic supramammillary
nucleus (SuM) sends long-range projections to hippocampal area CA2. While the SuM-CA2 …

[PDF][PDF] Physiological signature of memory age in the prefrontal-hippocampal circuit

Y Makino, D Polygalov, F Bolaņos, A Benucci… - Cell reports, 2019 - cell.com
… (Figure 3D). This was again not observed during the habituation session (Figure S3D) and
… comparable firing rates across sessions (Figure 3D). These results suggest that ACC may …

[PDF][PDF] CA2 inhibition reduces the precision of hippocampal assembly reactivation

…, R Boehringer, AJY Huang, ETN Overton, D Polygalov… - Neuron, 2021 - cell.com
… Data and code availability d All data reported in this paper are archived at the … d All code
used for analysis of this data is publicly available at https://zenodo.org/record/5250785. d Any …

[HTML][HTML] Stress enhances hippocampal neuronal synchrony and alters ripple-spike interaction

A Tomar, D Polygalov, S Chattarji, TJ McHugh - Neurobiology of Stress, 2021 - Elsevier
… 1D) with the difference being most pronounced during acute stress on the first day (acute-rest, …
4C and D), we did observe event specific increases in co-activity, which was also carried …

[HTML][HTML] Silencing CA1 pyramidal cells output reveals the role of feedback inhibition in hippocampal oscillations

…, J Joseph, G Foustoukos, J Wang, D Polygalov… - Nature …, 2024 - nature.com
d Configuration of whole cell voltage clamp recording in acute hippocampal slices
prepared from CaMKIIα:Cre mice previously injected with mCherry or TeTX.mCherry virus was …

The dynamic impact of repeated stress on the hippocampal spatial map

A Tomar, D Polygalov, S Chattarji, TJ McHugh - Hippocampus, 2015 - Wiley Online Library
… compared to the control mice (Figure 1D, Table 1). Further, this decrease in excitability
resulted in significantly smaller place fields (Figure 1D). This effect was also evident when we …

CA3 synaptic silencing attenuates kainic acid-induced seizures and hippocampal network oscillations

MY Lily, D Polygalov, ME Wintzer, MC Chiang… - eneuro, 2016 - eneuro.org
… and drug d [two-way ANOVA, F (1,21) (genotype × drug)=18.35, p=0.0003] and a significant
decrease in c-fos expression in KA-injected CA3-TeTX mice compared with controls d (…