Background This article provides an overview of the first BioASQ challenge, a competition on
large-scale biomedical semantic indexing and question answering (QA), which took place …

Comparative genomics has revealed a class of non-protein-coding genomic sequences that
display an extraordinary degree of conservation between two or more organisms, regularly …

The eukaryotic replisome is a crucial determinant of genome stability, but its structure is still
poorly understood. We found previously that many regulatory proteins assemble around the …

Resistance to EGFR inhibitors (EGFRi) presents a major obstacle in treating non-small cell
lung cancer (NSCLC). One of the most exciting new ways to find potential resistance markers …

We examined the role of repeat expansions in the pathogenesis of frontotemporal dementia
(FTD) and amyotrophic lateral sclerosis (ALS) by analyzing whole-genome sequence data …

Background Repeat expansion disorders affect about 1 in 3000 individuals and are clinically
heterogeneous diseases caused by expansions of short tandem DNA repeats. Genetic …

Objective Germline loss‐of‐function mutations in DEPDC5, and in its binding partners (NPRL2/3)
of the mammalian target of rapamycin (mTOR) repressor GATOR1 complex, cause …

This paper proposes guided self-scheduling, a new approach for scheduling arbitrarily
nested parallel program loops on shared memory multiprocessor systems. Utilizing loop …

Background This systematic literature review (SLR) analyzes migrant entrepreneurship
support in Europe through three research questions (RQs) to understand 1) migrant …

Purpose Biallelic variants in UCHL1 have been associated with a progressive early-onset
neurodegenerative disorder, autosomal recessive spastic paraplegia type 79. In this study, we …