There is an unmet clinical need for improved tissue and liquid biopsy tools for cancer detection.
We investigated the proteomic profile of extracellular vesicles and particles (EVPs) in …

Precision medicine is an approach that takes into account the influence of individuals' genes,
environment, and lifestyle exposures to tailor interventions. Here, we describe the …

Glioblastoma is one of the most challenging forms of cancer to treat. Here we describe a
computational platform that integrates the analysis of copy number variations and somatic …

… In accord with this prediction, we observe a large array of PCR bands upon 3C analysis (Figure
1D). These products were cloned into a plasmid vector, and individual clones were then …

The prognosis of patients with glioblastoma (GBM) remains dismal, with a median survival
of approximately 15 months. Current preclinical GBM models are limited by the lack of a "…

The development of effective therapies against brain metastasis is currently hindered by
limitations in our understanding of the molecular mechanisms driving it. Here we define the …

Vascular calcification is a hallmark of atherosclerosis. The location, density, and confluence
of calcification may change portions of the arterial conduit to a noncompliant structure. …

Glioblastomas (GBMs) diffusely infiltrate the brain, making complete removal by surgical
resection impossible. The mixture of neoplastic and nonneoplastic cells that remain after …

… (D and E) Adjacent coronal sections through amygdala of adult male bearing the modified
AR gene stained for PLAP (D) and β-gal (E) activity. Dorsal is to the top and midline is to the …

… as compared with 2-D and TO, including SOX4, BCAN, and genes encoding members of the
NOTCH pathway. Finally, we replated GLICO cells in 2-D culture conditions and show that a …