[PDF][PDF] Emerging biological principles of metastasis
AW Lambert, DR Pattabiraman, RA Weinberg - Cell, 2017 - cell.com
Metastases account for the great majority of cancer-associated deaths, yet this complex
process remains the least understood aspect of cancer biology. As the body of research …
process remains the least understood aspect of cancer biology. As the body of research …
Tackling the cancer stem cells—what challenges do they pose?
DR Pattabiraman, RA Weinberg - Nature reviews Drug discovery, 2014 - nature.com
Since their identification in 1994, cancer stem cells (CSCs) have been objects of intensive
study. Their properties and mechanisms of formation have become a major focus of current …
study. Their properties and mechanisms of formation have become a major focus of current …
Role and potential for therapeutic targeting of MYB in leukemia
DR Pattabiraman, TJ Gonda - Leukemia, 2013 - nature.com
The Myb protein was first identified as an oncogene that causes leukemia in chickens. Since
then, it has been widely associated with different types of cancers and studied in detail in …
then, it has been widely associated with different types of cancers and studied in detail in …
[PDF][PDF] Recovering gene interactions from single-cell data using data diffusion
… (D) FACS measurements of CD34 and FCGR3 protein levels versus transcript levels, before
and after MAGIC. Both FACS measurements and mRNA levels are log-scaled as per FACS …
and after MAGIC. Both FACS measurements and mRNA levels are log-scaled as per FACS …
Grid-forming inverters: A critical asset for the power grid
…, Z Chen, D Pattabiraman - IEEE Journal of Emerging …, 2019 - ieeexplore.ieee.org
Increasing inverter-based sources reduces the system's inertia resulting in possible frequency
stability issues. Understanding low-inertia systems and their stability properties is of …
stability issues. Understanding low-inertia systems and their stability properties is of …
The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy
…, F Reinhardt, OA Mercury, DR Pattabiraman… - Science translational …, 2018 - science.org
… (D to F) Tumor incidence as a function of time for three experiments in which tumors and
surgical wounds were inflicted at contralateral sites: (D) mice were wounded by sponge …
surgical wounds were inflicted at contralateral sites: (D) mice were wounded by sponge …
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells
…, DG Stover, DR Pattabiraman… - Proceedings of the …, 2017 - National Acad Sciences
… (D) Typical histogram of the SUM159 cells used to isolate ITGB4 hi and ITGB4 lo subpopulations.
(E) Western blots of fibronectin (FN1) and cytochrome c oxidase subunit 4I1 (COXIV) …
(E) Western blots of fibronectin (FN1) and cytochrome c oxidase subunit 4I1 (COXIV) …
Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
DR Pattabiraman, B Bierie, KI Kober, P Thiru, JA Krall… - Science, 2016 - science.org
… Pattabiraman et al. hypothesized that compounds that induce TICs to undergo a phenotypic
change called the mesenchymal-to-epithelial transition (MET) would therefore cause TICs to …
change called the mesenchymal-to-epithelial transition (MET) would therefore cause TICs to …
Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer
… (D) Lung sections collected at the time of maximum tumor burden (2 cm 3 ), with GFP-labeled
tumor cells, following orthotopic injections as in (A). (E) Lungs fixed and stained from (A) …
tumor cells, following orthotopic injections as in (A). (E) Lungs fixed and stained from (A) …
Comparison of grid following and grid forming control for a high inverter penetration power system
D Pattabiraman, RH Lasseter… - 2018 IEEE Power & …, 2018 - ieeexplore.ieee.org
The displacement of synchronous generators with inverter-based sources in the electric grid
can results in larger frequency deviations due to lower rotating inertial energy. Existing grid-…
can results in larger frequency deviations due to lower rotating inertial energy. Existing grid-…