[HTML][HTML] Evidence and role for bacterial mucin degradation in cystic fibrosis airway disease

JM Flynn, D Niccum, JM Dunitz, RC Hunter - PLoS pathogens, 2016 - journals.plos.org
Chronic lung infections in cystic fibrosis (CF) patients are composed of complex microbial
communities that incite persistent inflammation and airway damage. Despite the high density …

The stability of countercurrent mixing layers in circular jets

PJ Strykowski, DL Niccum - Journal of Fluid Mechanics, 1991 - cambridge.org
… < x/D < 0.17) the local velocity ratio varied between 1.43 d R,ocal < 1.56 or an average value
of 1.495. Therefore, the reference velocity ratio of R = 1.5 corresponds approximately to the …

The association of serum bilirubin levels on the outcomes of severe sepsis

JJ Patel, A Taneja, D Niccum, G Kumar… - Journal of intensive …, 2015 - journals.sagepub.com
Purpose: Admission serum bilirubin levels have been incorporated into severity of illness
scoring systems in critical illness as a marker of liver dysfunction. The purpose of our study is to …

[HTML][HTML] Interactions between the gut microbiome and host gene regulation in cystic fibrosis

G Dayama, S Priya, DE Niccum, A Khoruts… - Genome medicine, 2020 - Springer
… CST5, which encodes cytostatin D, is a direct target of p53 and vitamin D receptor and
promotes mesenchymal-epithelial transition to suppress tumor progression and metastasis [56]. …

[HTML][HTML] Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment

…, DE Niccum, A Khoruts, TK Starr, D Knights… - PLoS …, 2018 - journals.plos.org
Variation in the gut microbiome has been linked to colorectal cancer (CRC), as well as to host
genetic variation. However, we do not know whether, in addition to baseline host genetics, …

[HTML][HTML] Colonoscopic screening shows increased early incidence and progression of adenomas in cystic fibrosis

DE Niccum, JL Billings, JM Dunitz, A Khoruts - Journal of Cystic Fibrosis, 2016 - Elsevier
Background Colorectal cancer is an emerging problem in cystic fibrosis (CF). The goal of
this study was to evaluate adenoma detection by systematic colonoscopic screening and …

The influence of velocity and density ratio on the dynamics of spatially developing mixing layers

PJ Strykowski, DL Niccum - Physics of Fluids A: Fluid Dynamics, 1992 - pubs.aip.org
… can be found in Strykowski and Niccum3 and Niccum.) Husain and Hussain9 showed the …
in the potential core at x/D = 2. (The measurements were made at x/D = 2 to assure that the hot …

Evaluating yield of 19 versus 21 G EBUS-TBNA needles: a prospective study

FS Elmufdi, MK Peterson, D Niccum… - … of bronchology & …, 2021 - journals.lww.com
Background: Controversy remains regarding the effect of needle size on the diagnostic yield
of endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration. We …

Chromosomal changes detected by fluorescence in situ hybridization in patients with acute lymphoblastic leukemia

…, JB Parkhurst, WF Kern, KV Scott, D Niccum… - Chinese medical …, 2003 - mednexus.org
Objectives To investigate patients with acute lymphoblastic leukemia(ALL)for TEL/AML1 fusion,
BCR/ABL fusion, MLL gene rearrangements, and numerical changes of chromosomes 4, …

A new genomic duplication syndrome complementary to the velocardiofacial (22q11 deletion) syndrome

SJ Hassed, D Hopcus‐Niccum, L Zhang, S Li… - Clinical …, 2004 - Wiley Online Library
Fluorescence in situ hybridization (FISH) analysis can reveal undetected chromosomal
rearrangements. We report a patient with cleft palate, hydronephrosis, and minor dysmorphic …