User profiles for D. Merico
Daniele MericoVevo Tx / TCAG (SickKids) Verified email at vevo.ai Cited by 20588 |
A copy number variation map of the human genome
A major contribution to the genome variability among individuals comes from deletions and
duplications — collectively termed copy number variations (CNVs) — which alter the diploid …
duplications — collectively termed copy number variations (CNVs) — which alter the diploid …
Deep learning in biomedicine
… Daniele Merico … (d) Convolutional networks can learn to recognize patterns in
biological sequences such as regulatory elements. … Daniele Merico …
biological sequences such as regulatory elements. … Daniele Merico …
How to visually interpret biological data using networks
Networks in biology can appear complex and difficult to decipher. Merico et al. illustrate how
to interpret biological networks with the help of frequently used visualization and analysis …
to interpret biological networks with the help of frequently used visualization and analysis …
Functional impact of global rare copy number variation in autism spectrum disorders
The autism spectrum disorders (ASDs) are a group of conditions characterized by impairments
in reciprocal social interaction and communication, and the presence of restricted and …
in reciprocal social interaction and communication, and the presence of restricted and …
[HTML][HTML] Enrichment map: a network-based method for gene-set enrichment visualization and interpretation
Background Gene-set enrichment analysis is a useful technique to help functionally characterize
large gene lists, such as the results of gene expression experiments. This technique …
large gene lists, such as the results of gene expression experiments. This technique …
Pathway enrichment analysis and visualization of omics data using g: Profiler, GSEA, Cytoscape and EnrichmentMap
Pathway enrichment analysis helps researchers gain mechanistic insight into gene lists
generated from genome-scale (omics) experiments. This method identifies biological pathways …
generated from genome-scale (omics) experiments. This method identifies biological pathways …
[PDF][PDF] Convergence of genes and cellular pathways dysregulated in autism spectrum disorders
Rare copy-number variation (CNV) is an important source of risk for autism spectrum
disorders (ASDs). We analyzed 2,446 ASD-affected families and confirmed an excess of genic …
disorders (ASDs). We analyzed 2,446 ASD-affected families and confirmed an excess of genic …
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …
The human splicing code reveals new insights into the genetic determinants of disease
INTRODUCTION Advancing whole-genome precision medicine requires understanding
how gene expression is altered by genetic variants, especially those that are far outside of …
how gene expression is altered by genetic variants, especially those that are far outside of …
Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
We are performing whole-genome sequencing of families with autism spectrum disorder (ASD)
to build a resource (MSSNG) for subcategorizing the phenotypes and underlying genetic …
to build a resource (MSSNG) for subcategorizing the phenotypes and underlying genetic …