User profiles for D. Mas-Ponte
David Mas-PontePostdoc, University of Washington Verified email at uw.edu Cited by 640 |
LncATLAS database for subcellular localization of long noncoding RNAs
D Mas-Ponte, J Carlevaro-Fita, E Palumbo, TH Pulido… - Rna, 2017 - rnajournal.cshlp.org
… (D) Overview of the cell lines and cellular compartments available for lncRNA RCI
calculations. “LncRNA genes” column indicates the number of lncRNA for which the RCI could be …
calculations. “LncRNA genes” column indicates the number of lncRNA for which the RCI could be …
Spectrum of DNA mismatch repair failures viewed through the lens of cancer genomics and implications for therapy
D Mas-Ponte, M McCullough, F Supek - Clinical Science, 2022 - portlandpress.com
Genome sequencing can be used to detect DNA repair failures in tumors and learn about
underlying mechanisms. Here, we synthesize findings from genomic studies that examined …
underlying mechanisms. Here, we synthesize findings from genomic studies that examined …
[HTML][HTML] Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
… d Number of basepairs and number of overlapping hCIS for cancer driver protein-coding
genes (CGC), non-cancer driver protein-coding genes (nonCGC), cancer-related lncRNAs (…
genes (CGC), non-cancer driver protein-coding genes (nonCGC), cancer-related lncRNAs (…
DNA mismatch repair promotes APOBEC3-mediated diffuse hypermutation in human cancers
D Mas-Ponte, F Supek - Nature genetics, 2020 - nature.com
… d, Poisson mixture modeling of the number of A3-context mutations per cluster. A solution
with two distributions is shown (teal: kataegis; orange: omikli). The stacked bars show …
with two distributions is shown (teal: kataegis; orange: omikli). The stacked bars show …
[HTML][HTML] Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type
… c, d Linear fit with age (c) and yearly increase (d) of potentially pathogenic variants in KT2
vs KT1-SAT-VAT clones. Potentially pathogenic variants are defined as follows: all variants …
vs KT1-SAT-VAT clones. Potentially pathogenic variants are defined as follows: all variants …
[HTML][HTML] Passenger mutations accurately classify human tumors
M Salvadores, D Mas-Ponte… - PLoS computational …, 2019 - journals.plos.org
Determining the cancer type and molecular subtype has important clinical implications. The
primary site is however unknown for some malignancies discovered in the metastatic stage. …
primary site is however unknown for some malignancies discovered in the metastatic stage. …
Mutation rate heterogeneity at the sub-gene scale due to local DNA hypomethylation
D Mas-Ponte, F Supek - Nucleic Acids Research, 2024 - academic.oup.com
… Our brainenriched UMRs showed a less striking selectivity (Figure 3D). Overall, the variability
in local mutation rates at UMRs at the tissue level is explained both by the signatures the …
in local mutation rates at UMRs at the tissue level is explained both by the signatures the …
Sequence diversity of the Rh blood group system in Basques
A Flores-Bello, D Mas-Ponte, ME Rosu… - European Journal of …, 2018 - nature.com
… In particular, we genotyped the most relevant variants of the system (D/d, E/e, and C/c), and
sequenced three ~6 kb flanking regions surrounding the Rh genes in Basques and also in …
sequenced three ~6 kb flanking regions surrounding the Rh genes in Basques and also in …
[HTML][HTML] Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
…, A Lanzós, L Feuerbach, C Hong, D Mas-Ponte… - Communications …, 2022 - nature.com
In the published version of this paper, the members of the Pan-Cancer Analysis of Whole
Genomes (PCAWG) Consortium were listed in the Supplementary Information; however, these …
Genomes (PCAWG) Consortium were listed in the Supplementary Information; however, these …
[HTML][HTML] A maternal germline mutator phenotype in a family affected by heritable colorectal cancer
… as the “D” genotype, we added up mutations of type c from all mice with the “D” genotype and
… For the “D” allele and the BXD68 hypermutator allele, we divided the relative rate of each …
… For the “D” allele and the BXD68 hypermutator allele, we divided the relative rate of each …