NASP: an accurate, rapid method for the identification of SNPs in WGS datasets that supports flexible input and output formats
JW Sahl, D Lemmer, J Travis, JM Schupp… - Microbial …, 2016 - microbiologyresearch.org
Whole-genome sequencing (WGS) of bacterial isolates has become standard practice in
many laboratories. Applications for WGS analysis include phylogeography and molecular …
many laboratories. Applications for WGS analysis include phylogeography and molecular …
[HTML][HTML] Genomic Analysis of the Emergence and Rapid Global Dissemination of the Clonal Group 258 Klebsiella pneumoniae Pandemic
…, EM Driebe, DR MacCannell, C Roe, D Lemmer… - PloS one, 2015 - journals.plos.org
… deletion events result in conversion to a, c, d, and e subtypes. Sequential deletions could be
… or d to c or e, and c to e. However, selection may be against conversions from Tn4401a or d …
… or d to c or e, and c to e. However, selection may be against conversions from Tn4401a or d …
[HTML][HTML] Novel Odoribacter splanchnicus Strain and Its Outer Membrane Vesicles Exert Immunoregulatory Effects in vitro
…, V Kainulainen, JR Bowers, D Lemmer… - Frontiers in …, 2020 - frontiersin.org
… In section D, experiment refers to an individual biological experiment using a new passage
of HT-29 cells. Representative results are shown as a mean and standard deviation of three …
of HT-29 cells. Representative results are shown as a mean and standard deviation of three …
[HTML][HTML] Isolation of Anti-Inflammatory and Epithelium Reinforcing Bacteroides and Parabacteroides Spp. from A Healthy Fecal Donor
…, T Heini, JR Bowers, D Jasso-Selles, D Lemmer… - Nutrients, 2020 - mdpi.com
Altered intestinal microbiota is associated with systemic and intestinal diseases, such as
inflammatory bowel disease (IBD). Dysbiotic microbiota with enhanced proinflammatory …
inflammatory bowel disease (IBD). Dysbiotic microbiota with enhanced proinflammatory …
Rapid drug susceptibility testing of drug-resistant Mycobacterium tuberculosis isolates directly from clinical samples by use of amplicon sequencing: a proof-of-concept …
RE Colman, J Anderson, D Lemmer… - Journal of clinical …, 2016 - Am Soc Microbiol
Increasingly complex drug-resistant tuberculosis (DR-TB) is a major global health concern
and one of the primary reasons why TB is now the leading infectious cause of death …
and one of the primary reasons why TB is now the leading infectious cause of death …
[HTML][HTML] Whole-genome and targeted sequencing of drug-resistant Mycobacterium tuberculosis on the iSeq100 and MiSeq: A performance, ease-of-use, and cost …
…, J Hetzel, H Mshaiel, A Suresh, D Lemmer… - PLoS …, 2019 - journals.plos.org
Background Accurate, comprehensive, and timely detection of drug-resistant tuberculosis (TB)
is essential to inform patient treatment and enable public health surveillance. This is …
is essential to inform patient treatment and enable public health surveillance. This is …
[HTML][HTML] Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study
…, A Reuter, M Folkerts, C Allender, D Lemmer… - The Lancet …, 2023 - thelancet.com
Background Bedaquiline is a life-saving tuberculosis drug undergoing global scale-up. People
at risk of weak tuberculosis drug regimens are a priority for novel drug access despite the …
at risk of weak tuberculosis drug regimens are a priority for novel drug access despite the …
Mixed Mycobacterium tuberculosis–Strain Infections Are Associated With Poor Treatment Outcomes Among Patients With Newly Diagnosed Tuberculosis …
…, Y Baik, C Allender, D Lemmer… - The Journal of …, 2018 - academic.oup.com
Background Heteroresistant Mycobacterium tuberculosis infections (defined as concomitant
infection with drug-resistant and drug-susceptible strains) may explain the higher risk of …
infection with drug-resistant and drug-susceptible strains) may explain the higher risk of …
Direct detection of Coccidioides from Arizona soils using CocciENV, a highly sensitive and specific real-time PCR assay
Coccidioides immitis and Coccidioides posadasii are soil fungi endemic to desert regions of
the southwestern United States, and the causative agents of valley fever, or …
the southwestern United States, and the causative agents of valley fever, or …
Mycobacterium tuberculosis subculture results in loss of potentially clinically relevant heteroresistance
…, R Penaloza, C Allender, D Lemmer… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Multidrug-resistant tuberculosis (TB) presents a major public health dilemma. Heteroresistance,
the coexistence of drug-resistant and drug-susceptible strains or of multiple drug-…
the coexistence of drug-resistant and drug-susceptible strains or of multiple drug-…