The key–lock theory and the induced fit theory
DE Koshland Jr - Angewandte Chemie International Edition in …, 1995 - Wiley Online Library
… Koshland, Jr. Department of’ Molecular and Cell Biology University of California 229 Stanley
Hall 3206, Berkeley, CA … Koshland was born in New York City in 1920. He earned his B. S. …
Hall 3206, Berkeley, CA … Koshland was born in New York City in 1920. He earned his B. S. …
NO News Is Good News: a startlingly simple molecule unites neuroscience, physiology, and immunology and revises scientists' understanding of how cells …
E Culotta, DE Koshland Jr - Science, 1992 - science.org
NO News Is Good News Page 1 _MOLECULE OF THE YEAR NO News Is Good News ing
out how the enzyme works. NO cure for heartache. This year, clinical applications of NO …
out how the enzyme works. NO cure for heartache. This year, clinical applications of NO …
The catalytic and regulatory properties of enzymes
DE Koshland Jr, KE Neet - Annual review of biochemistry, 1968 - annualreviews.org
… KOSHLAND & NEET is occurring and which influences the binding or activity at this site
by in direct means. This definition would not only include the effects of M2 on the substrate of …
by in direct means. This definition would not only include the effects of M2 on the substrate of …
Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*
DE Koshland Jr, G Némethy, D Filmer - Biochemistry, 1966 - ACS Publications
DE Koshland, Jr., f G. Némethy, and D. Filmer abstract: Models for subunit interactions are
examined by means of interpreting ligand saturation curves. Equations are derived to indicate …
examined by means of interpreting ligand saturation curves. Equations are derived to indicate …
Application of a theory of enzyme specificity to protein synthesis
DE Koshland Jr - Proceedings of the National Academy of …, 1958 - National Acad Sciences
The suggestion of Lipmann'that the energy required to drive this reaction to the right came
from adenosine triphosphate has been supported by the extensive work2 which has been …
from adenosine triphosphate has been supported by the extensive work2 which has been …
A method for the quantitative modification and estimation of carboxylic acid groups in proteins
DG Hoare, DE Koshland - Journal of Biological Chemistry, 1967 - ASBMB
A method for the rapid modification under mild conditions of carboxyl groups in proteins has
been developed. The method involves the activation of the carboxyl group by a water-…
been developed. The method involves the activation of the carboxyl group by a water-…
An amplified sensitivity arising from covalent modification in biological systems.
A Goldbeter, DE Koshland Jr - Proceedings of the National …, 1981 - National Acad Sciences
The transient and steady-state behavior of a reversible covalent modification system is
examined. When the modifying enzymes operate outside the region of first-order kinetics, small …
examined. When the modifying enzymes operate outside the region of first-order kinetics, small …
The gradient-sensing mechanism in bacterial chemotaxis
RM Macnab, DE Koshland Jr - Proceedings of the National …, 1972 - National Acad Sciences
A “temporal gradient apparatus” has been developed that allows the motility of bacteria to be
studied after they have been subjected to a sudden change from one uniform concentration …
studied after they have been subjected to a sudden change from one uniform concentration …
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p.
…, JM Peters, MW Kirschner, D Koshland - Genes & …, 1996 - genesdev.cshlp.org
… We thank Andy Hoyt, Kim Nasmyth, David Pellman, and the members of the Koshland lab
for helpful discussions and critical reading of this manuscript. This work was supported by a …
for helpful discussions and critical reading of this manuscript. This work was supported by a …
[HTML][HTML] A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae
V Guacci, D Koshland, A Strunnikov - Cell, 1997 - cell.com
The S. cerevisiae MCD1(mitotic chromosome determinant) gene was identified in genetic
screens for genes important for chromosome structure. MCD1 is essential for viability and …
screens for genes important for chromosome structure. MCD1 is essential for viability and …