User profiles for D. Kingsley

David M Kingsley

Staff Scientist Tissue Engineer, Colossal Biosciences
Verified email at colossal.com
Cited by 382

[PDF][PDF] The TGF-b superfamily: new members, new receptors, and new genetic tests of function in different organisms

D Kingsley - Genes and development, 1994 - scholar.archive.org
In the last 10 years, a large family of secreted signaling molecules has been discovered that
appear to mediate many key events in normal growth and development. The family is known …

What do BMPs do in mammals? Clues from the mouse short-ear mutation

DM Kingsley - Trends in Genetics, 1994 - Elsevier
… The callus of skeletal precursor cells fllat forms 3 d after rib fracture is smaller in short-ear
(represented by stippled areas) than control long--ear (represented by filled areas) animals. …

[HTML][HTML] The genomic basis of adaptive evolution in threespine sticklebacks

…, ES Lander, F Di Palma, K Lindblad-Toh, DM Kingsley - Nature, 2012 - nature.com
Marine stickleback fish have colonized and adapted to thousands of streams and lakes
formed since the last ice age, providing an exceptional opportunity to characterize genomic …

Widespread parallel evolution in sticklebacks by repeated fixation of ectodysplasin alleles

…, J Schmutz, RM Myers, D Schluter, DM Kingsley - science, 2005 - science.org
… Olivera, and members of the Kingsley laboratory for generous help with fish collecting
and population samples; D. Schlessinger and V. Thermes for the pCI neo-Eda A1 and pISceI-…

Adaptive Evolution of Pelvic Reduction in Sticklebacks by Recurrent Deletion of a Pitx1 Enhancer

…, B Jónsson, D Schluter, MA Bell, DM Kingsley - science, 2010 - science.org
The molecular mechanisms underlying major phenotypic changes that have evolved
repeatedly in nature are generally unknown. Pelvic loss in different natural populations of …

[HTML][HTML] Recent advances in bioprinting and applications for biosensing

AD Dias, DM Kingsley, DT Corr - Biosensors, 2014 - mdpi.com
Future biosensing applications will require high performance, including real-time monitoring
of physiological events, incorporation of biosensors into feedback-based devices, detection …

Genetic and developmental basis of evolutionary pelvic reduction in threespine sticklebacks

…, KS Nereng, B Jónsson, D Schluter, DM Kingsley - Nature, 2004 - nature.com
Hindlimb loss has evolved repeatedly in many different animals by means of molecular
mechanisms that are still unknown. To determine the number and type of genetic changes …

Limb alterations in brachypodism mice due to mutations in a new member of the TGFβ-superfamily

…, TV Huynh, NG Copeland, NA Jenkins, DM Kingsley… - Nature, 1994 - nature.com
… We thank D. Sweatt for providing the protocol for the protein kinase assay, RY Tsien, DV
Madison and S. Siegelbaum for their … d, Autophosphorylation assay using highly purified …

Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis: pathogenetic and clinical implications

…, P Tofts, DG MacManus, BE Kendall, DPE Kingsley… - Brain, 1990 - academic.oup.com
From an extensive serial magnetic resonance imaging (MRI) study in multiple sclerosis (MS)
we have identified 4 cases in which disruption of the blood-brain barrier, as detected by …

Role of the Mouse ank Gene in Control of Tissue Calcification and Arthritis

AM Ho, MD Johnson, DM Kingsley - Science, 2000 - science.org
Mutation at the mouse progressive ankylosis(ank) locus causes a generalized, progressive
form of arthritis accompanied by mineral deposition, formation of bony outgrowths, and joint …