… Most molecular clock estimates use the mean d, but V(d) also exists, regardless of how d is
… any pair of sequences from any two taxa, estimate d, and calculate the time of divergence as: […

Let α= the probability of substitution from one nucleotide to another in one time click. By
hypothesis, whether it is a purinepurine, purine-pyrimidine, or pyrimidine-pyrimidine substitution, …

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model
organism for the study of generalized insect development, and an important pest of stored …

We report the sequence and analysis of the 814-megabase genome of the sea urchin
Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing …

To understand the biology and evolution of ruminants, the cattle genome was sequenced to
about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a …

We report here genome sequences and comparative analyses of three closely related
parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important …

… 1 B and C) shows that Hymenoptera and Coleoptera share more orthologs with the body
louse than they do with the fruit fly D. melanogaster. Relative to the well-studied D. …

Evaluating the accuracy of multiple sequence alignment (MSA) is critical for virtually every
comparative sequence analysis that uses an MSA as input. Here we present the GUIDANCE …

… and, then, thrown out a day before becoming useful” (Wool D, personal communication). …
DG wishes to express his awe and reverence at Eric D. Green's pioneering status as the first …

Background The first generation of genome sequence assemblies and annotations have had
a significant impact upon our understanding of the biology of the sequenced species, the …