… It was recently discovered that H2S can also be produced from d-cysteine involving 3-MST
and d-amino acid oxidase (81). In the kidney, more H2S is said to be produced from D-serine …

We tested the hypothesis that AMP-activated protein kinase (AMPK), an energy sensor,
regulates diabetes-induced renal hypertrophy. In kidney glomerular epithelial cells, high glucose …

… d-cysteine pathway is active at a pH of 7.4 compared to optimal pH of 8.4 for l-cysteine derived
H 2 S generation (ibid). Oral administration of d… 2 S; these data show that d-cysteine is an …

… Feliers and associates (33) have reported that ANG II promotes VEGF expression within
minutes of incubation in proximal tubular epithelial cells by promoting its translation. …

… -tubular debris (Figure 2d). Kidneys from PAD4KO mice subjected to I/R also showed evidence
of injury, but less than that seen in WT mice (Figure 2d). Semiquantitative assessment of …

Hydrogen sulfide, a signaling gas, affects several cell functions. We hypothesized that
hydrogen sulfide modulates high glucose (30 mm) stimulation of matrix protein synthesis in …

… Author links open overlay panel Denis Feliers 1 , Xiaoyan Chen 1 , Nese Akis , Goutam
Ghosh Choudhury , Michael Madaio , Balakuntalam S. … Feliers, S. Duraisamy, JL Barnes, et al. …

… This study was supported by JDRF Research Grant 1-2010-141 (to D. Feliers). The PAS
and Sirius red staining were performed by the Cancer Therapy and Research Center at the …

… The rapid phase synthesis of laminin-β1 was not associated with changes in mRNA level;
it could be blocked by cycloheximide but not by actinomycin D, suggesting regulation by …

Unilateral ureteral obstruction causes important tubulo-interstitial fibrosis in the kidney.
Metformin reduces fibrosis in mice with diabetic nephropathy. We examined the effects of …