User profiles for D. Dulin

David Dulin

VU Amsterdam – Physics of Living Systems
Verified email at vu.nl
Cited by 1519

Studying genomic processes at the single-molecule level: introducing the tools and applications

D Dulin, J Lipfert, MC Moolman, NH Dekker - Nature Reviews Genetics, 2013 - nature.com
D | The observation of transcription elongation by a single E. coli RNA Pol at base-pair … coli
ribosome, the authors attached the ribosome to a bead held in a micropipette (see panel d of …

Development and evaluation of sunlight actinometers

D Dulin, T Mill - Environmental Science & Technology, 1982 - ACS Publications
Background General Considerations. Estimation of the rate con-stant for photolysis in
sunlight (kpE) of a specific chemical in dilute aqueous solution requires information about the …

Double-stranded RNA under force and torque: similarities to and striking differences from double-stranded DNA

…, T Hensgens, T Jager, D Dulin… - Proceedings of the …, 2014 - National Acad Sciences
… Previous elastic models originally developed for dsDNA (44, 45) predict a positive twist–stretch
coupling for dsRNA, in agreement with our measurements for D RNA although at odds …

An optimized software framework for real-time, high-throughput tracking of spherical beads

JP Cnossen, D Dulin, NH Dekker - Review of Scientific Instruments, 2014 - pubs.aip.org
… (d) The computed quadrant radial profiles are combined and concatenated (indicated by
) to prepare for FFT autocorrelation. (e) The x and y profiles are convolved with their mirror …

Untangling reaction pathways through modern approaches to high-throughput single-molecule force-spectroscopy experiments

D Dulin, BA Berghuis, M Depken, NH Dekker - Current opinion in structural …, 2015 - Elsevier
… (d) A magnetic tweezers experiment that uses a pair of magnets to apply a force or torque
to a tethered molecule. The magnetic tweezers assay is readily parallelized, as shown in the …

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

…, Y Xiang, B Canard, M Depken, CE Cameron, D Dulin - Elife, 2021 - elifesciences.org
The absence of ‘shovel-ready’ anti-coronavirus drugs during vaccine development has
exceedingly worsened the SARS-CoV-2 pandemic. Furthermore, new vaccine-resistant variants …

[PDF][PDF] High spatiotemporal-resolution magnetic tweezers: calibration and applications for DNA dynamics

D Dulin, TJ Cui, J Cnossen, MW Docter, J Lipfert… - Biophysical journal, 2015 - cell.com
… In both (C) and (D), a laser is used to illuminate the field of view, resulting in an intensity of
150 gray levels on … 2 D). These steps are well defined in the raw data acquired at 6 kHz (Fig. 2 …

Biological magnetometry: torque on superparamagnetic beads in magnetic fields

…, LE Dickinson, F Pedaci, M Köber, D Dulin… - Physical review …, 2015 - APS
… (d) The limit of the SW model in which NPs behave like PDMs. (e) The special case of the
SW model in which the individual NPs behave like SPMs. (f) Model in which NPs are …

Effects of peripheral and central visual impairment on mental imagery capacity

D Dulin, Y Hatwell, Z Pylyshyn, S Chokron - Neuroscience & Biobehavioral …, 2008 - Elsevier
This paper reviews a number of behavioral, neuropsychological and neuroimaging studies
that bear on the question of whether and how visual disorders of peripheral or central origin …

[HTML][HTML] A force calibration standard for magnetic tweezers

Z Yu, D Dulin, J Cnossen, M Köber… - Review of Scientific …, 2014 - pubs.aip.org
To study the behavior of biological macromolecules and enzymatic reactions under force,
advances in single-molecule force spectroscopy have proven instrumental. Magnetic tweezers …