User profiles for D. DeTomaso

David DeTomaso

UC Berkeley
Verified email at berkeley.edu
Cited by 1326

[HTML][HTML] Solar wind electrons alphas and protons (SWEAP) investigation: Design of the solar wind and coronal plasma instrument suite for solar probe plus

…, G Dalton, B Dasgupta, D DeTomaso… - Space Science …, 2016 - Springer
The Solar Wind Electrons Alphas and Protons (SWEAP) Investigation on Solar Probe Plus
is a four sensor instrument suite that provides complete measurements of the electrons and …

[PDF][PDF] Metabolic modeling of single Th17 cells reveals regulators of autoimmunity

A Wagner, C Wang, J Fessler, D DeTomaso… - Cell, 2021 - cell.com
… (C and D) Density plot showing DFMO effects on transcriptome (C) and chromatin accessibility
(D). Genes or loci are divided into those upregulated or more accessible, respectively, in …

[HTML][HTML] Functional interpretation of single cell similarity maps

D DeTomaso, MG Jones, M Subramaniam… - Nature …, 2019 - nature.com
We present Vision, a tool for annotating the sources of variation in single cell RNA-seq data
in an automated and scalable manner. Vision operates directly on the manifold of cell-cell …

[PDF][PDF] Performance assessment and selection of normalization procedures for single-cell RNA-seq

MB Cole, D Risso, A Wagner, D DeTomaso, J Ngai… - Cell systems, 2019 - cell.com
… (D) PCA of the QC measures for all cells in (A). PCs of QC measures are labeled ‘‘qPCs’’ to
distinguish them from expression PCs. Single-cell QC profiles cluster by batch, representing …

[PDF][PDF] Hotspot identifies informative gene modules across modalities of single-cell genomics

D DeTomaso, N Yosef - Cell systems, 2021 - cell.com
DeTomaso and Yosef propose a novel, graph-based method for this purpose with improved
… Data and code availability d This paper analyzes existing, publicly available data. These …

[HTML][HTML] FastProject: a tool for low-dimensional analysis of single-cell RNA-Seq data

D DeTomaso, N Yosef - BMC bioinformatics, 2016 - Springer
… Let P(E ij ∣N o t D ij ) denote the probability that a gene i is expressed in cell j conditioned
… for the detection, P(D ij ), and expression, P(E ij ), events: For P(D ij ) we use the percentage …

Protein sialylation regulates a gene expression signature that promotes breast cancer cell pathogenicity

RA Kohnz, LS Roberts, D DeTomaso… - ACS chemical …, 2016 - ACS Publications
Many mechanisms have been proposed for how heightened aerobic glycolytic metabolism
fuels cancer pathogenicity, but there are still many unexplored pathways. Here, we have …

[HTML][HTML] Respiratory Management of the Preterm Infant: Supporting Evidence-Based Practice at the Bedside

…, A Lio, A Paladini, S Fattore, A Esposito, D De Tomaso… - Children, 2023 - mdpi.com
Extremely preterm infants frequently require some form of respiratory assistance to facilitate
the cardiopulmonary transition that occurs in the first hours of life. Current resuscitation …

In silico modeling of metabolic state in single Th17 cells reveals novel regulators of inflammation and autoimmunity

A Wagner, C Wang, D DeTomaso, J Avila-Pacheco… - bioRxiv, 2020 - biorxiv.org
… (D) Spearman correlation of Compass scores of single reactions with the expression of pro-…
Reactions are colored by the sign of their Cohen d’s statistic, and are opaque or transparent …

Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling

M Pawlak, D DeTomaso, A Schnell, GM Zu Horste… - Immunity, 2022 - cell.com
… ACA Computational analyses of single-cell and population RNA-seq data were performed
by D. DeTomaso and NY with additional help from SJR The manuscript was written by MP, D. …