… coli (DA Berthold and DA Day, unpublished results). Activity is also lost upon oxidation of
Cys I to form a disulfide bridge between the two subunits, and this mechanism serves to …

… behavior consistent with negative cooperativity, suggesting that binding the activator to one
subunit of the dimer may lower the affinity of the other subunit for the activator (DA Berthold, I. …

Background Abiraterone acetate plus prednisolone improves survival in men with relapsed
prostate cancer. We assessed the effect of this combination in men starting long-term …

Photosystem II of chloroplast thylakoid membranes provides light-generated oxidizing
equivalents which ultimately oxidize water to oxygen. The system is known to contain a reaction …

Purpose The TAX 327 study compared docetaxel administered every 3 weeks (D3), weekly
docetaxel (D1), and mitoxantrone (M), each with prednisone (P), in 1,006 men with …

Misfolded α-synuclein amyloid fibrils are the principal components of Lewy bodies and
neurites, hallmarks of Parkinson's disease (PD). We present a high-resolution structure of an α-…

… (D) Overall survival in the ADT with docetaxel population. n/N represents events/patients.
The number of events per patients in the radiotherapy subgroup analysis is not presented as …

… D, Heat map of cell density changes in tumors based on NanoString analysis. E, mIF imaging
reveals immune-cell infiltration in tumors at cycle 2, day 5 (20× magnification; DAPI nuclear …

Background There exists a vast number of surgical treatment options for acromioclavicular (AC)
joint injuries, and the current literature has yet to determine an equivocally superior …

… dark, (c) cell-free culture liquid in the light, (d) cell-free culture liquid in the dark and when …
1a–d). This suggests that the active compound is released during cultivation but not present …