[PDF][PDF] Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer
Inflammatory bowel disease is an important risk factor for colorectal cancer. We show that
sphingosine-1-phosphate (S1P) produced by upregulation of sphingosine kinase 1 (SphK1) …
sphingosine-1-phosphate (S1P) produced by upregulation of sphingosine kinase 1 (SphK1) …
[HTML][HTML] BRCA1 supports XIST RNA concentration on the inactive X chromosome
… (D–L) Combined immunostaining of telomerase-immortalized human mammary epithelial
cells (D–F) with a monoclonal antibody to BRCA1 (D) and a polyclonal antibody to MH2A1 (E). …
cells (D–F) with a monoclonal antibody to BRCA1 (D) and a polyclonal antibody to MH2A1 (E). …
Oligopyrimidine tract at the 5'end of mammalian ribosomal protein mRNAs is required for their translational control.
S Levy, D Avni, N Hariharan… - Proceedings of the …, 1991 - National Acad Sciences
Mammalian ribosomal protein (rp) mRNAs are subject to translational control, as illustrated
by their selective release from polyribosomes in growth-arrested cells and their …
by their selective release from polyribosomes in growth-arrested cells and their …
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer
Sphingosine-1-phosphate (S1P), a pleiotropic bioactive lipid mediator, and the kinase that
produces it have now emerged as key regulators of numerous cellular processes involved in …
produces it have now emerged as key regulators of numerous cellular processes involved in …
[HTML][HTML] Flavonoids-macromolecules interactions in human diseases with focus on Alzheimer, atherosclerosis and cancer
Flavonoids, a class of polyphenols, consumed daily in our diet, are associated with a reduced
risk for oxidative stress (OS)-related chronic diseases, such as cardiovascular disease, …
risk for oxidative stress (OS)-related chronic diseases, such as cardiovascular disease, …
[HTML][HTML] Regulation of cholesterol metabolism by phytochemicals derived from algae and edible mushrooms in non-alcoholic fatty liver disease
…, N Pintel, H Khattib, N Shagug, R Taha, D Avni - International Journal of …, 2022 - mdpi.com
… In another randomized controlled clinical trial in which children with NAFLD (classified by
biopsy) participated, the addition of 2000 IU per day of vitamin D for 6 months was associated …
biopsy) participated, the addition of 2000 IU per day of vitamin D for 6 months was associated …
[HTML][HTML] Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors
…, BJ Scicluna, RA Sharples, A Waltmann, D Avni… - Nature …, 2017 - nature.com
… d Pathway analysis of mRNA targets of miRNA differentially detected in EVs from iRBCs.
Ingenuity Pathway Analysis 75 was used to find direct and indirect relationships, with the …
Ingenuity Pathway Analysis 75 was used to find direct and indirect relationships, with the …
Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory
… The mice were then given a daily acquisition session for 5 d (SCID) or 10 d (WT and Sphk2
−/− ) to locate the submerged platform that remained in a fixed location. Testing sessions …
−/− ) to locate the submerged platform that remained in a fixed location. Testing sessions …
[HTML][HTML] Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 …
… (D) The expression levels of four miRNAs from the chromosome-14q32-cluster in normal
melanocytes (NHEM), benign nevi (NEV) and melanoma samples (MEL) using qRT-PCR. Data …
melanocytes (NHEM), benign nevi (NEV) and melanoma samples (MEL) using qRT-PCR. Data …
The 5′ terminal oligopyrimidine tract confers translational control on TOP mRNAs in a cell type-and sequence context-dependent manner
… observed that poly(A)-binding protein, a new member of the TOP mRNA family, is translationally
controlled with a different cell specificity (D. Avni and O. Meyuhas, unpublished data). …
controlled with a different cell specificity (D. Avni and O. Meyuhas, unpublished data). …