Insights into the mechanisms of eukaryotic translation gained with ribosome profiling

DE Andreev, PBF O'Connor, G Loughran… - Nucleic acids …, 2017 - academic.oup.com
… (D) Site specific pause originating from ribosomes stalled within acORF at a specific location.
(E) Ribosomes paused at the stop codon and queued upstream ribosomes; green and blue …

Cap-and IRES-independent scanning mechanism of translation initiation as an alternative to the concept of cellular IRESs

IN Shatsky, SE Dmitriev, IM Terenin, DE Andreev - Molecules and cells, 2010 - Springer
… papers published during last four years (Andreev et al., 2009; Baranick et al., 2008; Bert
et al., 2006; Young et al., 2008). They are summarized in our recent report (Andreev et al., …

[HTML][HTML] Non-AUG translation initiation in mammals

DE Andreev, G Loughran, AD Fedorova… - Genome Biology, 2022 - Springer
Recent proteogenomic studies revealed extensive translation outside of annotated protein
coding regions, such as non-coding RNAs and untranslated regions of mRNAs. This non-…

Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

DE Andreev, PBF O'Connor, C Fahey, EM Kenny… - elife, 2015 - elifesciences.org
10.7554/eLife.03971.001 Eukaryotic cells rapidly reduce protein synthesis in response to
various stress conditions. This can be achieved by the phosphorylation-mediated inactivation …

[HTML][HTML] 2020 Clinical guidelines for Atrial fibrillation and atrial flutter

…, AV Shpektor, DA Andreev… - Russian Journal of …, 2021 - russjcardiol.elpub.ru
… DA Andreev … Maintenance of sinus rhythm with oral d,l-sotalol therapy in patients with
symptomatic … Mozaffarian D, Furberg CD, Psaty BM, Siscovick D. Physical activity and incidenceof …

Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2

IM Terenin, SE Dmitriev, DE Andreev… - Nature structural & …, 2008 - nature.com
… (d) 80S complexes formed with GMPPNP, 40S, 60S, eIF3 and eIF5B or with omission of one
… 1c,d). The 80S complexes thus formed are fully competent for translation … Dmitry E Andreev

[PDF][PDF] αCaMKII is essential for cerebellar LTD and motor learning

…, SH Houtman, GHS Buitendijk, D Andreev… - Neuron, 2006 - cell.com
… Cerebellar Morphology Is Normal in aCaMKII2/2 Mutants (A–D) Thionin staining of sagittal …
D) mice reveals a normal overall morphology of the cerebellum of aCaMKII2/2 mice. (C and D

[HTML][HTML] Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin

D Andreev, M Liu, D Weidner, K Kachler… - The Journal of …, 2020 - Am Soc Clin Investig
… (D) Representative TRAP staining in tibial sections of the aforementioned 2 groups. Dark …
, 4 days after ip injection with 100 ng DT and (D) quantification of BV/TV, Tb.N, Tb.Sp, and Tb.…

[HTML][HTML] GTP-independent tRNA delivery to the ribosomal P-site by a novel eukaryotic translation factor

SE Dmitriev, IM Terenin, DE Andreev, PA Ivanov… - Journal of Biological …, 2010 - ASBMB
During translation, aminoacyl-tRNAs are delivered to the ribosome by specialized GTPases
called translation factors. Here, we report the tRNA binding to the P-site of 40 S ribosomes …

Alternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells

…, KS Anufrieva, J Wang, VO Shender, DE Andreev… - Nature cell …, 2022 - nature.com
Glioblastoma (GBM) is characterized by exceptionally high intratumoral heterogeneity.
However, the molecular mechanisms underlying the origin of different GBM cell populations …