User profiles for D. Agudelo

Daniel Agudelo

Université Laval
Verified email at ulaval.ca
Cited by 1989

[HTML][HTML] Review on the binding of anticancer drug doxorubicin with DNA and tRNA: Structural models and antitumor activity

D Agudelo, P Bourassa, G Bérubé… - … of Photochemistry and …, 2016 - Elsevier
In this review, we have compared the results of multiple spectroscopic studies and molecular
modeling of anticancer drug doxorubicin (DOX) bindings to DNA and tRNA. DOX was …

An overview on the delivery of antitumor drug doxorubicin by carrier proteins

D Agudelo, G Bérubé, HA Tajmir-Riahi - International journal of biological …, 2016 - Elsevier
Serum proteins play an increasing role as drug carriers in the clinical settings. In this review,
we have compared the binding modalities of anticancer drug doxorubicin (DOX) to three …

Intercalation of antitumor drug doxorubicin and its analogue by DNA duplex: structural features and biological implications

D Agudelo, P Bourassa, G Bérubé… - International journal of …, 2014 - Elsevier
The intercalation of antitumor drug doxorubicin (DOX) and its analogue N-(trifluoroacetyl)
doxorubicin (FDOX) with DNA duplex was investigated, using FTIR, CD, fluorescence …

Effect of polymer molecular weight on chitosan–protein interaction

L Bekale, D Agudelo, HA Tajmir-Riahi - Colloids and Surfaces B …, 2015 - Elsevier
We present a comprehensive study of the interactions between chitosan nanoparticles (15,
100 and 200 kDa with the same degree of deacetylation 90%) and two model proteins, ie, …

[HTML][HTML] Smell and taste dysfunction in COVID-19 is associated with younger age in ambulatory settings: a multicenter cross-sectional study.

…, B Mateos-Serrano, D Agudelo… - J Investig Allergol …, 2020 - pesquisa.bvsalud.org
OBJECTIVE: Since the initial anecdotal reports of coronavirus disease 2019 (COVID-19)
from China, a growing number of studies have reported on smell and/or taste dysfunction (STD)…

[HTML][HTML] Probing the Binding Sites of Antibiotic Drugs Doxorubicin and N-(trifluoroacetyl) Doxorubicin with Human and Bovine Serum Albumins

D Agudelo, P Bourassa, J Bruneau, G Berube… - 2012 - journals.plos.org
… and presence of quencher, [Q] is the quencher concentration and K D is the Stern-Volmer
quenching constant (K q ), which can be written as K D = k q t 0 ; where k q is the bimolecular …

Marker-free coselection for CRISPR-driven genome editing in human cells

D Agudelo, A Duringer, L Bozoyan, CC Huard… - Nature …, 2017 - nature.com
… was performed 10 d later to determine the frequency of indels, as indicated at the base of
each lane. Where indicated, cells were treated with 0.5 μM ouabain for 7 d starting 3 d after …

[HTML][HTML] Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins

AP Hynes, GM Rousseau, D Agudelo, A Goulet… - Nature …, 2018 - nature.com
CRISPR-Cas systems are bacterial anti-viral systems, and bacterial viruses (bacteriophages,
phages) can carry anti-CRISPR (Acr) proteins to evade that immunity. Acrs can also fine-…

Encapsulation of antitumor drug doxorubicin and its analogue by chitosan nanoparticles

S Sanyakamdhorn, D Agudelo… - …, 2013 - ACS Publications
Biodegradable chitosan of different sizes were used to encapsulate antitumor drug doxorubicin
(Dox) and its N-(trifluoroacetyl) doxorubicin (FDox) analogue. The complexation of Dox …

The role of polymer size and hydrophobic end-group in PEG–protein interaction

L Bekale, D Agudelo, HA Tajmir-Riahi - Colloids and Surfaces B …, 2015 - Elsevier
We investigated the interaction between polyethylene (glycol) (PEG) and human (HSA) and
bovine serum albumin (BSA) in aqueous solution, using multiple spectroscopic methods and …