User profiles for D. W. Logan

Darren Logan

VP Research, Mars Inc.
Verified email at effem.com
Cited by 7660

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

…, J Mill, RA Hachem, H Matsunami, DW Logan… - Science …, 2020 - science.org
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2) – the causal agent in COVID-19 – affects …

[PDF][PDF] Adipocyte accumulation in the bone marrow during obesity and aging impairs stem cell-based hematopoietic and bone regeneration

…, AM Jank, C Bocian, L Woelk, H Fan, DW Logan… - Cell stem cell, 2017 - cell.com
Aging and obesity induce ectopic adipocyte accumulation in bone marrow cavities. This
process is thought to impair osteogenic and hematopoietic regeneration. Here we specify the …

Identification of protein pheromones that promote aggressive behaviour

P Chamero, TF Marton, DW Logan, K Flanagan… - Nature, 2007 - nature.com
Mice use pheromones, compounds emitted and detected by members of the same species,
as cues to regulate social behaviours such as pup suckling, aggression and mating 1 . …

[HTML][HTML] Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes

…, MA Mahajan, B Yalcin, D Tannahill, DW Logan… - Cell, 2013 - cell.com
Mutations in whole organisms are powerful ways of interrogating gene function in a realistic
context. We describe a program, the Sanger Institute Mouse Genetics Project, that provides …

[HTML][HTML] The vomeronasal organ mediates interspecies defensive behaviors through detection of protein pheromone homologs

F Papes, DW Logan, L Stowers - Cell, 2010 - cell.com
Potential predators emit uncharacterized chemosignals that warn receiving species of
danger. Neurons that sense these stimuli remain unknown. Here we show that detection and …

[PDF][PDF] Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients

D Brann, T Tsukahara, C Weinreb, DW Logan… - BioRxiv, 2020 - biorxiv.org
Recent reports suggest an association between COVID-19 and altered olfactory function.
Here we analyze bulk and single cell RNA-Seq datasets to identify cell types in the olfactory …

Regulation of pigmentation in zebrafish melanophores

DW Logan, SF Burn, IJ Jackson - Pigment cell research, 2006 - Wiley Online Library
In comparison with the molecular genetics of melanogenesis in mammals, the regulation of
pigmentation in poikilothermic vertebrates is poorly understood. Mammals undergo …

Sexual dimorphism in olfactory signaling

L Stowers, DW Logan - Current opinion in neurobiology, 2010 - Elsevier
What makes males and females behave differently? Although genetic master-regulators
commonly underlie physical differences, sexually dimorphic behavior is additionally influenced …

[PDF][PDF] Murine pheromone proteins constitute a context-dependent combinatorial code governing multiple social behaviors

…, TH Kuo, A Cichy, S Dey, C Hays, M Kateri, DW Logan… - Cell, 2014 - cell.com
During social interactions, an individual's behavior is largely governed by the subset of
signals emitted by others. Discrimination of "self" from "other" regulates the territorial urine …

[PDF][PDF] Cyclic regulation of sensory perception by a female hormone alters behavior

…, MS Chien, X Ibarra-Soria, KR Spencer, DW Logan… - Cell, 2015 - cell.com
Females may display dramatically different behavior depending on their state of ovulation.
This is thought to occur through sex-specific hormones acting on behavioral centers in the …