… DT is funded by a grant from the Spanish Ministry of Economy and Competitiveness and
FEDER/UE (SAF2015-74072-JIN). MG is supported by the NHGRI under award number …

Every tumour is different. They arise in patients with different genomes, from cells with
different epigenetic modifications, and by random processes affecting the genome and/or …

Precision oncology relies on accurate discovery and interpretation of genomic variants,
enabling individualized diagnosis, prognosis and therapy selection. We found that six prominent …

… Author Contributions: Drs Benary and Rieke had full access to all of … Dr Benary, Mr Wang,
Dr Leser, and Dr Rieke contributed … Dr Rieke reported receiving consulting, advisory board, or …

Objective We present the Berlin-Tübingen-Oncology corpus (BRONCO), a large and freely
available corpus of shuffled sentences from German oncological discharge summaries …

CIViC (Clinical Interpretation of Variants in Cancer; civicdb.org) is a crowd-sourced, public
domain knowledgebase composed of literature-derived evidence characterizing the clinical …

Purpose Precision oncology holds the promise of improving patient outcome. It is based on
the idea that the testing of genomic biomarkers can lead to the recommendation of a …

Background The national Network Genomic Medicine (nNGM) Lung Cancer provides
comprehensive and high-quality multiplex molecular diagnostics and standardized personalized …

Head and neck squamous cell carcinoma (HNSCC) is one of the most common solid
cancers worldwide. It is mainly caused by exposure to tobacco smoke and alcohol as well as …

… The average number of molecular alterations per patient was 8 in the study by Rieke et al.
and 2.6 in the study by Koopman et al. In the here presented study, more than 300 alterations …