User profiles for D. R. Nyholt
Dale R NyholtProfessor of Biomedical Sciences, Queensland University of Technology Verified email at qut.edu.au Cited by 63338 |
Analysis of shared heritability in common disorders of the brain
…, N Eriksson, J Olesen, DI Chasman, DR Nyholt… - Science, 2018 - science.org
INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …
Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets
BACKGROUND Endometriosis is a heritable common gynaecological condition influenced
by multiple genetic and environmental factors. Genome-wide association studies (GWASs) …
by multiple genetic and environmental factors. Genome-wide association studies (GWASs) …
The search for genes contributing to endometriosis risk
GW Montgomery, DR Nyholt, ZZ Zhao… - Human reproduction …, 2008 - academic.oup.com
BACKGROUND Genetic variation contributes to the risk of developing endometriosis. This
review summarizes gene mapping studies in endometriosis and the prospects of finding gene …
review summarizes gene mapping studies in endometriosis and the prospects of finding gene …
Common SNPs explain a large proportion of the heritability for human height
…, BP McEvoy, S Gordon, AK Henders, DR Nyholt… - Nature …, 2010 - nature.com
… Dale R Nyholt … Jian Yang, Beben Benyamin, Brian P McEvoy, Scott Gordon, Anjali K Henders,
Dale R Nyholt, Nicholas G Martin, Grant W Montgomery & Peter M Visscher … Dale R Nyholt …
Dale R Nyholt, Nicholas G Martin, Grant W Montgomery & Peter M Visscher … Dale R Nyholt …
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Most common human traits and diseases have a polygenic pattern of inheritance: DNA
sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA…
sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA…
[PDF][PDF] A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
DR Nyholt - The American Journal of Human Genetics, 2004 - cell.com
… Address for correspondence and reprints: Dr. Dale R. Nyholt, Queensland Institute of
Medical Research, Post Office Royal Brisbane Hospital, Brisbane QLD 4029, Australia. E-mail: …
Medical Research, Post Office Royal Brisbane Hospital, Brisbane QLD 4029, Australia. E-mail: …
Defining the role of common variation in the genomic and biological architecture of adult human height
…, IM Leach, C Medina-Gomez, MA Nalls, DR Nyholt… - Nature …, 2014 - nature.com
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …
significance that together explained one-fifth of the heritability for adult height. By testing …
Genome-wide association study identifies 74 loci associated with educational attainment
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …