Family size, infection and atopy: the first decade of the'hygiene hypothesis'

DP Strachan - Thorax, 2000 - ncbi.nlm.nih.gov
… of effect modification (Butland BK, Strachan from maternal IgG is still … DP, unpublished
analyses: available on request). Thus, it … 104 Strachan DP. Time trends in asthma and allergy: ten …

Summary of effects of parental smoking on the respiratory health of children and implications for research

DG Cook, DP Strachan - Thorax, 1999 - thorax.bmj.com
… David P Strachan … Carey IM, Cook DG, Strachan DP. The effects of passive smoke exposure
assessed by questionnaire and salivary cotinine on lung function in a longitudinal study of …

Time trends in allergic disorders in the UK

R Gupta, A Sheikh, DP Strachan, HR Anderson - Thorax, 2007 - thorax.bmj.com
Background: Allergic disorders are common in the UK. This study reviews recent UK time
trends in the prevalence, morbidity and mortality for allergic disorders, excluding asthma. …

Hay fever, hygiene, and household size.

DP Strachan - BMJ: British Medical Journal, 1989 - ncbi.nlm.nih.gov
… Department of Epidemiology and Population Sciences, London School of Hygiene and
Tropical Medicine, London WC1E 7HT David P Strachan , MRCP, lecturer in epidemiology …

Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat …

…, S Montefort, B Björkstén, CKW Lai, DP Strachan… - The lancet, 2006 - thelancet.com
Background Data for trends in prevalence of asthma, allergic rhinoconjunctivitis, and eczema
over time are scarce. We repeated the International Study of Asthma and Allergies in …

[HTML][HTML] A large-scale, consortium-based genomewide association study of asthma

…, IG Gut, F Demenais, DP Strachan… - … England Journal of …, 2010 - Mass Medical Soc
Background Susceptibility to asthma is influenced by genes and environment; implicated
genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful in …

Common variants near MC4R are associated with fat mass, weight and risk of obesity

…, X Yuan, E Zeggini, JN Hirschhorn, DP Strachan… - Nature …, 2008 - nature.com
To identify common variants influencing body mass index (BMI), we analyzed genome-wide
association data from 16,876 individuals of European descent. After previously reported …

Genome-wide association study identifies eight loci associated with blood pressure

…, TD Spector, J Tuomilehto, D Altshuler, DP Strachan… - Nature …, 2009 - nature.com
Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

…, L Kappos, C Polman, WL McArdle, DP Strachan… - Nature …, 2009 - nature.com
We report the results of a meta-analysis of genome-wide association scans for multiple
sclerosis (MS) susceptibility that includes 2,624 subjects with MS and 7,220 control subjects. …

Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors

P Patel, MA Mendall, D Carrington, DP Strachan… - Bmj, 1995 - bmj.com
Objective: To investigate the relation between seropositivity to chronic infections with
Helicobacter pylori and Chlamydia pneumoniae and both coronary heart disease and …