Members of the family Herpesviridae have enveloped, spherical virions with characteristic
complex structures consisting of symmetrical and non-symmetrical components. The linear, …

TriTrypDB ( http://tritrypdb.org ) is an integrated database providing access to genome-scale
datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by …

Leishmania parasites cause a broad spectrum of clinical disease. Here we report the
sequencing of the genomes of two species of Leishmania: Leishmania infantum and Leishmania …

Primary varicella-zoster virus (VZV) infection causes varicella (chickenpox) and the establishment
of a lifelong latent infection in ganglionic neurons. VZV reactivates in about one-third …

Leishmania parasites cause a spectrum of clinical pathology in humans ranging from
disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference …

The rapid identification of antimicrobial resistance is essential for effective treatment of
highly resistant Mycobacterium tuberculosis . Whole-genome sequencing provides …

Whole genome sequencing of viruses directly from clinical samples is integral for understanding
the genetics of host-virus interactions. Here, we report the use of sample sparing target …

Transcriptome profiling has become routine in studies of many biological processes. However,
the favored approaches such as short-read Illumina RNA sequencing are giving way to …

Characterizing complex viral transcriptomes by conventional RNA sequencing approaches
is complicated by high gene density, overlapping reading frames, and complex splicing …

Modification of mRNA by N 6-adenosine methylation (m 6 A) on internal bases influences
gene expression in eukaryotes. How the dynamic genome-wide landscape of m 6 A-modified …