User profiles for D. N. Nesbeth
Darren N. NesbethAssociate Professor, Department of Biochemical Engineering, University College London Verified email at ucl.ac.uk Cited by 668 |
Synthetic biology routes to bio-artificial intelligence
… This scheme is proposed here by AZ and DN and the simulation was performed by CG and
… This scheme is proposed here by AZ and DN and the simulation was performed by CG and …
… This scheme is proposed here by AZ and DN and the simulation was performed by CG and …
[HTML][HTML] Differential Endocytic Functions ofTrypanosoma brucei Rab5 Isoforms Reveal a Glycosylphosphatidylinositol-specific Endosomal Pathway
A Pal, BS Hall, DN Nesbeth, HI Field… - Journal of Biological …, 2002 - ASBMB
We demonstrate the presence of a glycosylphosphatidylinositol (GPI) anchor-specific
endosomal pathway in the protozoan pathogen Trypanosoma brucei. In higher eukaryotes …
endosomal pathway in the protozoan pathogen Trypanosoma brucei. In higher eukaryotes …
Growth and productivity impacts of periplasmic nuclease expression in an Escherichia coli Fab' fragment production strain
DN Nesbeth, MA Perez‐Pardo, S Ali… - Biotechnology and …, 2012 - Wiley Online Library
Host cell engineering is becoming a realistic option in whole bioprocess strategies to maximize
product manufacturability. High molecular weight (MW) genomic DNA currently hinders …
product manufacturability. High molecular weight (MW) genomic DNA currently hinders …
Identification of black sturgeon caviar pigment as eumelanin
L Panzella, K Benning, DN Nesbeth, B Setaro… - Food Chemistry, 2022 - Elsevier
Reported herein is the purification of the pigment of black sturgeon caviar and its unambiguous
identification as a typical eumelanin by means of chemical degradation coupled with …
identification as a typical eumelanin by means of chemical degradation coupled with …
[PDF][PDF] Serum-free lentiviral vector production is compatible with medium-resident nuclease activity arising from adherent HEK293T host cells engineered with a …
…, J Ward, E Keshavarz-Moore, C Mason, DN Nesbeth - Heliyon, 2023 - cell.com
At present lentiviral vector production for cell and gene therapy commonly involves transient
plasmid transfection of mammalian cells cultivated in serum-containing media and addition …
plasmid transfection of mammalian cells cultivated in serum-containing media and addition …
Proteasome and thiol involvement in quality control of glycosylphosphatidylinositol anchor addition
B WILBOURN, DN Nesbeth… - Biochemical …, 1998 - portlandpress.com
Improperly processed secretory proteins are degraded by a hydrolytic system that is
associated with the endoplasmic reticulum (ER) and appears to involve re-export of lumenal …
associated with the endoplasmic reticulum (ER) and appears to involve re-export of lumenal …
Engineering an Autonucleolytic Mammalian Suspension Host Cell Line to Reduce DNA Impurity Levels in Serum-Free Lentiviral Process Streams
…, E Keshavarz-Moore, C Mason, DN Nesbeth - ACS Synthetic …, 2024 - ACS Publications
We engineered HEK293T cells with a transgene encoding tetracycline-inducible expression
of a Staphylococcus aureus nuclease incorporating a translocation signal. We adapted the …
of a Staphylococcus aureus nuclease incorporating a translocation signal. We adapted the …
Promoter engineering to optimize recombinant periplasmic Fab′ fragment production in Escherichia coli
…, A Templar, J Newton, DN Nesbeth - Biotechnology …, 2016 - Wiley Online Library
… The Nesbeth et al.25 procedure was used to assay total and extracellular dimeric Fab’ …
HPLC data gathered during this study and the studies of Balasundaram et al.28 and Nesbeth et al.…
HPLC data gathered during this study and the studies of Balasundaram et al.28 and Nesbeth et al.…
Correction: Proteasome and thiol involvement in quality control of glycosylphosphatidylinositol anchor addition
B Wilbourn, DN Nesbeth, LJ Wainwright… - Biochemical …, 2024 - portlandpress.com
The authors of the original article “Proteasome and thiol involvement in quality control of
glycosylphosphatidylinositol anchor addition” DOI: 10.1042/bj3320111: Wilbourn et al., Biochem…
glycosylphosphatidylinositol anchor addition” DOI: 10.1042/bj3320111: Wilbourn et al., Biochem…
[HTML][HTML] Open source approaches to establishing Roseobacter clade bacteria as synthetic biology chassis for biogeoengineering
…, W Beaufoy, S Rose, T Ratisai, A Zaikin, DN Nesbeth - PeerJ, 2016 - peerj.com
… Cite this article Borg Y, Grigonyte AM, Boeing P, Wolfenden B, Smith P, Beaufoy W, Rose
S, Ratisai T, Zaikin A, Nesbeth DN. Open source approaches to establishing Roseobacter …
S, Ratisai T, Zaikin A, Nesbeth DN. Open source approaches to establishing Roseobacter …