Cytoplasmic accumulation and nuclear clearance of TDP-43 characterize familial and sporadic
forms of amyotrophic lateral sclerosis and frontotemporal lobar degeneration, suggesting …

Drosophila models of Parkinson's disease are characterized by two principal phenotypes:
the specific loss of dopaminergic (DA) neurons in the aging brain and defects in motor …

Accumulation and aggregation of TDP-43 is a major pathological hallmark of amyotrophic
lateral sclerosis and frontotemporal dementia. TDP-43 inclusions also characterize patients …

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are
neurodegenerative disorders that are characterized by cytoplasmic aggregates and nuclear …

• The clinicopathologic features of nine cases of sinonasal tract leiomyosarcoma (SNTL)
referred to the Armed Forces Institute of Pathology, Washington, DC, during the period from …

UCP1 catalyzes proton leak across the mitochondrial inner membrane to disengage substrate
oxidation from ATP production. It is well established that UCP1 is activated by fatty acids …

Mitochondrial dysfunction is commonly observed in degenerative disorders, including
Alzheimer's and Parkinson's disease that are characterized by the progressive and selective loss …

Mucolipidosis type IV (MLIV) is a lysosomal storage disease caused by mutations in the
MCOLN1 gene, which encodes the lysosomal transient receptor potential ion channel mucolipin-…

Intradermal injection of 0.1 pmole (52 pg.) of acetyl glyceryl ether phosphorylcholine (AGEPC)
in guinea pigs induced increased vascular permeability as assessed by a skin-blueing …

The potent vasoactive and leukotactic properties of acetyl glyceryl ether phosphorylcholine (AGEPC)
were further characterized histologically. After intravenous infusion of colloidal …