Bipolar affective disorders linked to DNA markers on chromosome 11

JA Egeland, DS Gerhard, DL Pauls, JN Sussex… - Nature, 1987 - nature.com
Pauls", James N. Sussex", Kenneth K. Kidd", Cleona R. … Jefferson, JW, Greist, JH,
Ackerman, DL & Carroll, JA Lithium Encyclopedia for Clinical Practice (American Psychiatric …

Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective

DL Pauls, A Abramovitch, SL Rauch… - Nature Reviews …, 2014 - nature.com
Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and behaviours
that are experienced as unwanted. Family and twin studies have demonstrated that OCD …

Obsessive-compulsive disorder phenotypes: implications for genetic studies

…, AG Hounie, MT Mercadante, P Chacon, DL Pauls - Molecular …, 2005 - nature.com
Obsessive-compulsive disorder (OCD) clinical presentation is remarkably diverse, and can
vary both within and across patients over time. This variability in the phenotypic expression …

Sequence Variants in SLITRK1 Are Associated with Tourette's Syndrome

…, AA Stillman, TM Morgan, CA Mathews, DL Pauls… - Science, 2005 - science.org
Tourette's syndrome (TS) is a genetically influenced developmental neuropsychiatric disorder
characterized by chronic vocal and motor tics. We studied Slit and Trk-like 1 (SLITRK1) as …

A family study of obsessive-compulsive disorder.

DL Pauls, JP Alsobrook 2nd, W Goodman… - The American journal …, 1995 - europepmc.org
Objective The goal of this study was to determine 1) whether obsessive-compulsive
disorder is familial, 2) whether there is a familial relationship between obsessive-compulsive …

[PDF][PDF] Symptoms of obsessive-compulsive disorder

…, WK Goodman, CJ McDougle, DL Pauls - American Journal of …, 1997 - researchgate.net
Obiective: Obsessive-conpulsive disorder encompasses a broad range of symptoms that rep-resent
multiple psychological domains, including perception, cognition, emotion, social …

Susceptibility loci for distinct components of developmental dyslexia on chromosomes 6 and 15.

…, LA Hart, WC Speed, A Shuster, DL Pauls - American journal of …, 1997 - ncbi.nlm.nih.gov
… Shuster,2 and DL Pauls,'13 … David Pauls, Child Study Center, Yale University School of
Medicine, 230 South Frontage Road, New Haven, CT 06520. E-mail: david.pauls@yale.edu © …

Gilles de la Tourette's syndrome and obsessive-compulsive disorder: Evidence supporting a genetic relationship

DL Pauls, KE Towbin, JF Leckman… - Archives of general …, 1986 - jamanetwork.com
… The methods have been described in detail by Pauls et al.16 Probands with TS were randomly
ascertained from the membership of the Connecticut Tourette Syndrome Association. The …

Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome

ME Hirschtritt, PC Lee, DL Pauls, Y Dion… - JAMA …, 2015 - jamanetwork.com
Importance Tourette syndrome (TS) is characterized by high rates of psychiatric comorbidity;
however, few studies have fully characterized these comorbidities. Furthermore, most …

[PDF][PDF] Disruption of neurexin 1 associated with autism spectrum disorder

…, K Tsatsanis, DJ Harris, I Noens, DL Pauls… - The American Journal of …, 2008 - cell.com
Autism is a neurodevelopmental disorder of complex etiology in which genetic factors play a
major role. We have implicated the neurexin 1 (NRXN1) gene in two independent subjects …