User profiles for D. L. DeMeo
 | Dawn L. DeMeoVerified email at channing.harvard.edu Cited by 22736 |
Sex and gender: modifiers of health, disease, and medicine
Clinicians can encounter sex and gender disparities in diagnostic and therapeutic responses.
These disparities are noted in epidemiology, pathophysiology, clinical manifestations, …
These disparities are noted in epidemiology, pathophysiology, clinical manifestations, …
α1-Antitrypsin deficiency· 2: Genetic aspects of α1-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk
DL DeMeo, EK Silverman - Thorax, 2004 - thorax.bmj.com
The genetic aspects of AAT deficiency and the variable manifestations of lung disease in PI
Z individuals are reviewed. The role of modifying genetic factors which may interact with …
Z individuals are reviewed. The role of modifying genetic factors which may interact with …
Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan
The traditional view of chronic obstructive pulmonary disease (COPD) as a self-inflicted disease
caused by tobacco smoking in genetically susceptible individuals has been challenged …
caused by tobacco smoking in genetically susceptible individuals has been challenged …
[HTML][HTML] Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
The Trans-Omics for Precision Medicine (TOPMed) programme seeks to elucidate the genetic
architecture and biology of heart, lung, blood and sleep disorders, with the ultimate goal of …
architecture and biology of heart, lung, blood and sleep disorders, with the ultimate goal of …
[PDF][PDF] DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis
Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
Epigenetic signatures of cigarette smoking
Background— DNA methylation leaves a long-term signature of smoking exposure and is one
potential mechanism by which tobacco exposure predisposes to adverse health outcomes…
potential mechanism by which tobacco exposure predisposes to adverse health outcomes…
[HTML][HTML] Transmission of lymphocytic choriomeningitis virus by organ transplantation
Background In December 2003 and April 2005, signs and symptoms suggestive of infection
developed in two groups of recipients of solid-organ transplants. Each cluster was …
developed in two groups of recipients of solid-organ transplants. Each cluster was …
[HTML][HTML] MMP12, Lung Function, and COPD in High-Risk Populations
Background Genetic variants influencing lung function in children and adults may ultimately
lead to the development of chronic obstructive pulmonary disease (COPD), particularly in …
lead to the development of chronic obstructive pulmonary disease (COPD), particularly in …
Variants in FAM13A are associated with chronic obstructive pulmonary disease
We performed a genome-wide association study for chronic obstructive pulmonary disease (COPD)
in three population cohorts, including 2,940 cases and 1,380 controls who were …
in three population cohorts, including 2,940 cases and 1,380 controls who were …
Clinical and radiologic disease in smokers with normal spirometry
…, HU Kauczor, WC Bailey, DL DeMeo… - JAMA internal …, 2015 - jamanetwork.com
Importance Airflow obstruction on spirometry is universally used to define chronic obstructive
pulmonary disease (COPD), and current or former smokers without airflow obstruction may …
pulmonary disease (COPD), and current or former smokers without airflow obstruction may …