[HTML][HTML] Cortisol and major depressive disorder—translating findings from humans to animal models and back

LS Nandam, M Brazel, M Zhou, DJ Jhaveri - Frontiers in psychiatry, 2020 - frontiersin.org
… LSN, MB, MZ, and DJ conducted critical evaluation of literature and contributed to the draft
… This work was supported by Mater Foundation Fellowship to DJ. We thank Rowan Tweedale …

[HTML][HTML] A comparative study of techniques for differential expression analysis on RNA-Seq data

ZH Zhang, DJ Jhaveri, VM Marshall, DC Bauer… - PloS one, 2014 - journals.plos.org
Recent advances in next-generation sequencing technology allow high-throughput cDNA
sequencing (RNA-Seq) to be widely applied in transcriptomic studies, in particular for …

Norepinephrine directly activates adult hippocampal precursors via β3-adrenergic receptors

DJ Jhaveri, EW Mackay, AS Hamlin… - Journal of …, 2010 - Soc Neuroscience
Adult hippocampal neurogenesis is a critical form of cellular plasticity that is greatly influenced
by neural activity. Among the neurotransmitters that are widely implicated in regulating …

[HTML][HTML] Dissecting the role of adult hippocampal neurogenesis towards resilience versus susceptibility to stress-related mood disorders

KL Jones, M Zhou, DJ Jhaveri - npj Science of Learning, 2022 - nature.com
Adult hippocampal neurogenesis in the developmental process of generating and integrating
new neurons in the hippocampus during adulthood and is a unique form of structural …

[HTML][HTML] Evidence for newly generated interneurons in the basolateral amygdala of adult mice

DJ Jhaveri, A Tedoldi, S Hunt, R Sullivan… - Molecular …, 2018 - nature.com
New neurons are continually generated from the resident populations of precursor cells in
selective niches of the adult mammalian brain such as the hippocampal dentate gyrus and the …

Stress and epilepsy: towards understanding of neurobiological mechanisms for better management

DJ Jhaveri, A McGonigal, C Becker, JJ Benoliel… - eneuro, 2023 - eneuro.org
Stress has been identified as a major contributor to human disease and is postulated to play
a substantial role in epileptogenesis. In a significant proportion of individuals with epilepsy, …

SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus

S Saharan, DJ Jhaveri… - Journal of Neuroscience …, 2013 - Wiley Online Library
Within the two neurogenic niches of the adult mammalian brain, ie, the subventricular zone
lining the lateral ventricle and the subgranular zone of the hippocampus, there exist distinct …

Purification of neural precursor cells reveals the presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus

DJ Jhaveri, I O'Keeffe, GJ Robinson… - Journal of …, 2015 - Soc Neuroscience
The activity of neural precursor cells in the adult hippocampus is regulated by various stimuli;
however, whether these stimuli regulate the same or different precursor populations …

[HTML][HTML] Opposing effects of α2-and β-adrenergic receptor stimulation on quiescent neural precursor cell activity and adult hippocampal neurogenesis

DJ Jhaveri, I Nanavaty, BW Prosper, S Marathe… - PloS one, 2014 - journals.plos.org
Norepinephrine regulates latent neural stem cell activity and adult hippocampal neurogenesis,
and has an important role in modulating hippocampal functions such as learning, …

Ubiquitination of the GluA1 subunit of AMPA receptors is required for synaptic plasticity, memory, and cognitive flexibility

…, M Ringuet, DG Blackmore, DJ Jhaveri… - Journal of …, 2023 - Soc Neuroscience
Activity-dependent changes in the number of AMPA-type glutamate receptors (AMPARs) at
the synapse underpin the expression of LTP and LTD, cellular correlates of learning and …