As the database of protein sequences grows it is becoming apparent that many proteins are
constructed from relatively few modular units that appear many times. Determination of the …

CBS domains are defined as sequence motifs that occur in several different proteins in all
kingdoms of life. Although thought to be regulatory, their exact functions have been unknown. …

Background: The activation of protein kinase B (PKB, also known as c-Akt) is stimulated by
insulin or growth factors and results from its phosphorylation at Thr308 and Ser473. We …

Repeat tracts of guanine bases found in DNA and RNA can form tetraplex structures in the
presence of a variety of monovalent cations. Evidence suggests that guanine tetraplexes …

… very similar for both methods,and in the following discussion only the results from the DG/SA
calculations are described in detail. A total of 459 distance restraints was used for the final …

We have found that the efficiency of fluorescence resonance energy transfer between Cy3
and Cy5 terminally attached to the 5′ ends of a DNA duplex is significantly affected by the …

We have determined the tertiary structure of box 2 from hamster HMG1 using bacterial expression
and 3D NMR. The all β-helical fold is in the form of a V-shaped arrowhead with helices …

The complement control protein (CCP) modules (also known as short consensus repeats) are
defined by a consensus sequence within a stretch of about 60 amino acid residues. These …

A large number of macrocyclic miniproteins with diverse biological activities have been isolated
from the Rubiaceae, Violaceae, and Cucurbitaceae plant families in recent years. Here …

Fluorescence resonance energy transfer provides valuable long-range distance information
about macromolecules in solution. Fluorescein and Cy3 are an important donor−acceptor …