Total knee replacement in the morbidly obese: a literature review
AJ Samson, GE Mercer, DG Campbell - ANZ journal of surgery, 2010 - Wiley Online Library
Background: The ‘obesity epidemic’ is expected to result in an increased incidence of knee
osteoarthritis and hence total knee replacements (TKRs). Reviews have demonstrated the …
osteoarthritis and hence total knee replacements (TKRs). Reviews have demonstrated the …
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
…, N Zhang, HI Woodroof, DG Campbell… - Open …, 2012 - royalsocietypublishing.org
Missense mutations in PTEN-induced kinase 1 (PINK1) cause autosomal-recessive inherited
Parkinson's disease (PD). We have exploited our recent discovery that recombinant insect …
Parkinson's disease (PD). We have exploited our recent discovery that recombinant insect …
Identification of the sites in MAP kinase kinase‐1 phosphorylated by p74raf‐1.
Many growth factors whose receptors are protein tyrosine kinases stimulate the MAP kinase
pathway by activating first the GTP‐binding protein Ras and then the protein kinase p74raf‐1…
pathway by activating first the GTP‐binding protein Ras and then the protein kinase p74raf‐1…
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
…, C Kondapalli, R Gourlay, DG Campbell… - Biochemical …, 2014 - portlandpress.com
We have previously reported that the Parkinson's disease-associated kinase PINK1 (PTEN-induced
putative kinase 1) is activated by mitochondrial depolarization and stimulates the …
putative kinase 1) is activated by mitochondrial depolarization and stimulates the …
Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins
MAP kinase‐activated protein kinase‐2 (MAPKAP kinase‐2) phosphorylates the serine
residues in murine heat shock protein 25 (hsp25) and human heat shock protein 27 (hsp27) …
residues in murine heat shock protein 25 (hsp25) and human heat shock protein 27 (hsp27) …
Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities
S Dowler, RA CURRIE, DG CAMPBELL… - Biochemical …, 2000 - portlandpress.com
The second messenger phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P 3 ] is
generated by the action of phosphoinositide 3-kinase (PI 3-kinase), and regulates a plethora of …
generated by the action of phosphoinositide 3-kinase (PI 3-kinase), and regulates a plethora of …
Prevalence of depression–PTSD comorbidity: Implications for clinical practice guidelines and primary care-based interventions
DG Campbell, BL Felker, CF Liu, EM Yano… - Journal of general …, 2007 - Springer
BACKGROUND Compared to those with depression alone, depressed patients with
posttraumatic stress disorder (PTSD) experience more severe psychiatric symptomatology and …
posttraumatic stress disorder (PTSD) experience more severe psychiatric symptomatology and …
LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity
M Jaleel, RJ Nichols, M Deak, DG Campbell… - Biochemical …, 2007 - portlandpress.com
Mutations in the LRRK2 (leucine-rich repeat kinase-2) gene cause late-onset PD (Parkinson's
disease). LRRK2 contains leucine-rich repeats, a GTPase domain, a COR [C-terminal of …
disease). LRRK2 contains leucine-rich repeats, a GTPase domain, a COR [C-terminal of …
14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking
…, BHC Wong, NT Wood, DG Campbell… - Biochemical …, 2004 - portlandpress.com
14-3-3-interacting proteins were isolated from extracts of proliferating HeLa cells using 14-3-3
affinity chromatography, eluting with a phosphopeptide that competes with targets for 14-3-…
affinity chromatography, eluting with a phosphopeptide that competes with targets for 14-3-…
MAPKAP kinase‐2; a novel protein kinase activated by mitogen‐activated protein kinase.
D Stokoe, DG Campbell, S Nakielny, H Hidaka… - The EMBO …, 1992 - embopress.org
A novel protein kinase, which was only active when phosphorylated by the mitogen‐activated
protein kinase (MAP kinase), has been purified 85,000‐fold to homogeneity from rabbit …
protein kinase (MAP kinase), has been purified 85,000‐fold to homogeneity from rabbit …