User profiles for D. E. Wildman

Derek Wildman

Professor, University of South Florida
Verified email at health.usf.edu
Cited by 11501

Accelerated evolution of the electron transport chain in anthropoid primates

LI Grossman, DE Wildman, TR Schmidt… - TRENDS in Genetics, 2004 - cell.com
Mitochondria are both the power plant of the cell and a central integrator of signals that
govern the lifespan, replication and death of the cell. Perhaps as a consequence, genes that …

Molecular evolution tracks macroevolutionary transitions in Cetacea

MR McGowen, J Gatesy, DE Wildman - Trends in ecology & evolution, 2014 - cell.com
Cetacea (whales, dolphins, and porpoises) is a model group for investigating the molecular
signature of macroevolutionary transitions. Recent research has begun to reveal the …

[HTML][HTML] Cytochrome c oxidase: evolution of control via nuclear subunit addition

D Pierron, DE Wildman, M Hüttemann… - … et Biophysica Acta (BBA …, 2012 - Elsevier
According to theory, present eukaryotic cells originated from a beneficial association between
two free-living cells. Due to this endosymbiotic event the pre-eukaryotic cell gained access …

Epigenetic and immune function profiles associated with posttraumatic stress disorder

M Uddin, AE Aiello, DE Wildman… - Proceedings of the …, 2010 - National Acad Sciences
The biologic underpinnings of posttraumatic stress disorder (PTSD) have not been fully
elucidated. Previous work suggests that alterations in the immune system are characteristic of …

Prolonged myelination in human neocortical evolution

…, AMM Sousa, N Šestan, DE Wildman… - Proceedings of the …, 2012 - National Acad Sciences
Nerve myelination facilitates saltatory action potential conduction and exhibits spatiotemporal
variation during development associated with the acquisition of behavioral and cognitive …

Metabolic costs and evolutionary implications of human brain development

…, O Muzik, PR Hof, DE Wildman… - Proceedings of the …, 2014 - National Acad Sciences
The high energetic costs of human brain development have been hypothesized to explain
distinctive human traits, including exceptionally slow and protracted preadult growth. Although …

[HTML][HTML] Largest GWAS of PTSD (N= 20 070) yields genetic overlap with schizophrenia and sex differences in heritability

…, JA Sumner, M Uddin, RJ Ursano, DE Wildman… - Molecular …, 2018 - nature.com
The Psychiatric Genomics Consortium-Posttraumatic Stress Disorder group (PGC-PTSD)
combined genome-wide case–control molecular genetic data across 11 multiethnic studies to …

Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: Enlarging genus Homo

DE Wildman, M Uddin, G Liu… - Proceedings of the …, 2003 - National Acad Sciences
What do functionally important DNA sites, those scrutinized and shaped by natural selection,
tell us about the place of humans in evolution? Here we compare ≈90 kb of coding DNA …

Evolution of increased glia–neuron ratios in the human frontal cortex

…, MA Raghanti, DE Wildman… - Proceedings of the …, 2006 - National Acad Sciences
… Amid calls for police officers to de-escalate encounters with Black citizens, this work sheds …
leaders alike have highlighted the need to de-escalate police encounters with the public. This …

Evolution of the mammalian placenta revealed by phylogenetic analysis

DE Wildman, C Chen, O Erez… - Proceedings of the …, 2006 - National Acad Sciences
The placenta is essential for the success of therian mammalian reproduction. Intense
selective pressure has shaped changes in placental anatomy and function during mammalian …