[HTML][HTML] Deeply altered genome architecture in the endoparasitic flowering plant Sapria himalayana Griff.(Rafflesiaceae)
Despite more than 2,000-fold variation in genome size, key features of genome architecture
are largely conserved across angiosperms. Parasitic plants have elucidated the many ways …
are largely conserved across angiosperms. Parasitic plants have elucidated the many ways …
Single-molecule sequencing resolves the detailed structure of complex satellite DNA loci in Drosophila melanogaster
DE Khost, DG Eickbush, AM Larracuente - Genome research, 2017 - genome.cshlp.org
… We determine the optimal de novo assembly methods and parameter combinations
required to produce a high-quality assembly of these previously unassembled satDNA loci and …
required to produce a high-quality assembly of these previously unassembled satDNA loci and …
Evolution of genome structure in the Drosophila simulans species complex
M Chakraborty, CH Chang, DE Khost… - Genome …, 2021 - genome.cshlp.org
… We generated highly contiguous de novo reference genomes for the Drosophila simulans
… We assembled the nuclear genomes of the sim-complex species de novo following the …
… We assembled the nuclear genomes of the sim-complex species de novo following the …
Dynamic Evolution of Euchromatic Satellites on the X Chromosome in Drosophila melanogaster and the simulans Clade
JS Sproul, DE Khost, DG Eickbush… - Molecular biology …, 2020 - academic.oup.com
Satellite DNAs (satDNAs) are among the most dynamically evolving components of
eukaryotic genomes and play important roles in genome regulation, genome evolution, and …
eukaryotic genomes and play important roles in genome regulation, genome evolution, and …
Expanding on Our Knowledge of Ecdysozoan Genomes: A Contiguous Assembly of the Meiofaunal Priapulan Tubiluchus corallicola
…, BAS de Medeiros, S Sato, DE Khost… - Genome Biology and …, 2023 - academic.oup.com
Genomic data for priapulans are limited to a single species, restricting broad comparative
analyses and thorough interrogation of questions spanning phylogenomics, ecdysozoan …
analyses and thorough interrogation of questions spanning phylogenomics, ecdysozoan …
Sizing Up the Onychophoran Genome: Repeats, Introns, and Gene Family Expansion Contribute to Genome Gigantism in Epiperipatus broadwayi
…, TJ Cunha, BAS De Medeiros, DE Khost… - Genome Biology and …, 2023 - academic.oup.com
Genome assemblies are growing at an exponential rate and have proved indispensable for
studying evolution but the effort has been biased toward vertebrates and arthropods with a …
studying evolution but the effort has been biased toward vertebrates and arthropods with a …
Single molecule long read sequencing resolves the detailed structure of complex satellite DNA loci in Drosophila melanogaster
DE Khost, D Eickbush, AM Larracuente - bioRxiv, 2016 - biorxiv.org
… We compared de novo PacBio assemblies generated using different methods and parameters
(both … We generated de novo PacBio-only assemblies using the Celera 8.3 and 8.2 PBcR …
(both … We generated de novo PacBio-only assemblies using the Celera 8.3 and 8.2 PBcR …
[BOOK][B] Structure and Dynamics of Satellite DNA Evolution in Drosophila melanogaster and the simulans Clade
DE Khost - 2019 - search.proquest.com
… We experiment with three different PacBio de novo assembly pipelines: Celera 8.1 (PBcR-BLASR),
Celera 8.3 (PBcR-MHAP), and Canu to assemble satDNA regions in the pericentric …
Celera 8.3 (PBcR-MHAP), and Canu to assemble satDNA regions in the pericentric …
Are chemical inhibitors an effective way to study the role of Cyclin Dependent Kinase 5 (CDK5) in neuronal and pancreatic development? Comparative kinase assays …
DE Khost, A Aguanno - 2011 - Wiley Online Library
Cyclin Dependent Kinase 5 (CDK5) is a member of the cyclin‐dependent kinase family of
proteins, which are the main regulators of the cell cycle. CDK5 is distinguished from its fellow …
proteins, which are the main regulators of the cell cycle. CDK5 is distinguished from its fellow …
Insulin disregulation and neurodegeneration: a possible role for CDK5
DE Khost, R Cotton, A Aguanno - 2012 - Wiley Online Library
Cyclin dependent kinase 5 (CDK5) is a member of the cyclin dependent kinase family that,
unlike its fellow CDKs, is not involved in regulation of the cell cycle, but is instead …
unlike its fellow CDKs, is not involved in regulation of the cell cycle, but is instead …