Horizontal gene transfer (HGT) is one of the most important evolutionary forces within
microbial populations. Although evidence for beneficial fitness effects of HGT is overwhelming, …

Phytopathogens coordinate multifaceted life histories and deploy stratified virulence
determinants via complex, global regulation networks. We dissect the global regulation of four …

… assembly of UB246, and anchor points were identified through inspection of identical
contigs from genome sequences for closely related strains (DA Baltrus, unpublished data). …

Closely related pathogens may differ dramatically in host range, but the molecular, genetic,
and evolutionary basis for these differences remains unclear. In many Gram- negative …

… Three lanes of Solexa sequencing of DC3000 whole DNA were also provided (Baltrus et al.,
unpublished data) and used for test assembly. All lanes combined were 202 884 352 bases …

Helicobacter pylori is a gram-negative pathogen that colonizes the stomachs of over half the
world's population and causes a spectrum of gastric diseases including gastritis, ulcers, and …

We developed a novel approach for de novo genome assembly using only sequence data
from high-throughput short read sequencing technologies. By combining data generated from …

The soft-agar overlay technique was originally developed over 70 years ago and has been
widely used in several areas of microbiological research, including work with bacteriophages …

… are closely related: their 16S rRNA sequences are 100% identical, and their whole-genome
sequences are nearly invariant (DA Baltrus, K. Dougherty, KR Arendt, M. Huntemann, A. …

… With an apparent molecular weight ‘clearly larger’ than 300 × 10 6 Da—which is
approximately 450 kb—they termed these elements megaplasmids. The term has persisted, and …