User profiles for C. van Oosterhout

C van Oosterhout

Professor in Evolutionary Genetics, UEA
Verified email at uea.ac.uk
Cited by 20079

Genetic load: genomic estimates and applications in non-model animals

…, E Trucchi, HE Morales, C van Oosterhout - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This ‘genetic load’ has been …

microchecker: software for identifying and correcting genotyping errors in microsatellite data

C Van Oosterhout, WF Hutchinson… - Molecular ecology …, 2004 - Wiley Online Library
DNA degradation, low DNA concentrations and primer‐site mutations may result in the incorrect
assignment of microsatellite genotypes, potentially biasing population genetic analyses. …

Balancing selection, random genetic drift, and genetic variation at the major histocompatibility complex in two wild populations of guppies (Poecilia reticulata)

C Van Oosterhout, DA Joyce, SM Cummings, J Blais… - …, 2006 - Wiley Online Library
… Linkage between loci was simulated using recombination coefficient (c) varying between c
… Cable, J., and C. van Oosterhout. 2006. The role of innate and acquired resistance in two …

Inbreeding depression and genetic load of sexually selected traits: how the guppy lost its spots

C Van Oosterhout, RE Trigg… - Journal of …, 2003 - academic.oup.com
To date, few studies have investigated the effects of inbreeding on sexually selected traits,
although inbreeding depression on such traits can play an important role in the evolution and …

Structural, stratigraphic and sedimentological characterisation of a wide rift system: The Triassic rift system of the Central Atlantic Domain

S Leleu, AJ Hartley, C van Oosterhout, L Kennan… - Earth-Science …, 2016 - Elsevier
… Hartley b , Cees van Oosterhout c , Lorcan Kennan c , Katrin Ruckwied c , Keith Gerdes c
Basin (Balkwill and Legall, 1989, modified); (C) Orpheus Basin to Abenaki Basin; (D) Orpheus …

[HTML][HTML] Purging and accumulation of genetic load in conservation

…, C Grossen, L Dalén, C van Oosterhout - Trends in Ecology & …, 2023 - cell.com
Our ability to assess the threat posed by the genetic load to small and declining populations
has been greatly improved by advances in genome sequencing and computational …

Real‐time genomics for One Health

…, Z Libke, G Erkenswick, C Van Oosterhout - Molecular Systems …, 2023 - embopress.org
… All these developments are shifting the dynamic co-evolutionary equilibria in favor of
pathogens (van Oosterhout, 2021), putting severe pressure on our society and environment, both …

[HTML][HTML] Estimates of Genetic Differentiation Measured by FST Do Not Necessarily Require Large Sample Sizes When Using Many SNP Markers

EM Willing, C Dreyer, C Van Oosterhout - 2012 - journals.plos.org
Population genetic studies provide insights into the evolutionary processes that influence
the distribution of sequence variants within and among wild populations. F ST is among the …

Estimation and adjustment of microsatellite null alleles in nonequilibrium populations

C Van Oosterhout, D Weetman… - Molecular Ecology …, 2006 - Wiley Online Library
Nonamplified (null) alleles are a common feature of microsatellite genotyping and can bias
estimates of allele and genotype frequencies, thereby hindering population genetic analyses. …

[HTML][HTML] Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus

…, C Bowler, BR Green, V Moulton, C Van Oosterhout… - Nature, 2017 - nature.com
… Sea ice is characterized by temperatures under 0 C, high salinity and, owing to the semi-enclosed
pore system within the ice, low diffusion rates of dissolved gases and exchange of …