User profiles for C. Yau
Christopher YauUniversity of Oxford Verified email at wrh.ox.ac.uk Cited by 8809 |
[HTML][HTML] Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension
The CONSORT 2010 statement provides minimum guidelines for reporting randomised trials.
Its widespread use has been instrumental in ensuring transparency in the evaluation of …
Its widespread use has been instrumental in ensuring transparency in the evaluation of …
[HTML][HTML] Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension
The SPIRIT 2013 statement aims to improve the completeness of clinical trial protocol
reporting by providing evidence-based recommendations for the minimum set of items to be …
reporting by providing evidence-based recommendations for the minimum set of items to be …
Bayesian statistics and modelling
… c–e | The prior and posterior distributions for β intercept (part c), the linear effect of age (years),
β age (part d) and \({\beta }_{{{\rm{age}}}^{2}}\) (part e) are shown. For each chain, the first …
β age (part d) and \({\beta }_{{{\rm{age}}}^{2}}\) (part e) are shown. For each chain, the first …
[PDF][PDF] The immune landscape of cancer
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising
33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we …
33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we …
[PDF][PDF] An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
…, P Spellman, C Benz, JM Stuart, CK Wong, C Yau… - Cell, 2018 - cell.com
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic
annotation data along with multi-platform molecular profiles of more than 11,000 human tumors …
annotation data along with multi-platform molecular profiles of more than 11,000 human tumors …
[PDF][PDF] Oncogenic signaling pathways in the cancer genome atlas
Genetic alterations in signaling pathways that control cell-cycle progression, apoptosis, and
cell growth are common hallmarks of cancer, but the extent, mechanisms, and co-…
cell growth are common hallmarks of cancer, but the extent, mechanisms, and co-…
[PDF][PDF] Driver fusions and their implications in the development and treatment of human cancers
Gene fusions represent an important class of somatic alterations in cancer. We systematically
investigated fusions in 9,624 tumors across 33 cancer types using multiple fusion calling …
investigated fusions in 9,624 tumors across 33 cancer types using multiple fusion calling …
[PDF][PDF] Comprehensive characterization of cancer driver genes and mutations
Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced
algorithms to identify drivers now exist, but systematic attempts to combine and optimize them on …
algorithms to identify drivers now exist, but systematic attempts to combine and optimize them on …
[PDF][PDF] Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer
We conducted comprehensive integrative molecular analyses of the complete set of tumors
in The Cancer Genome Atlas (TCGA), consisting of approximately 10,000 specimens and …
in The Cancer Genome Atlas (TCGA), consisting of approximately 10,000 specimens and …
[PDF][PDF] Comprehensive molecular portraits of invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, …
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, …