User profiles for C. Várnai
Csilla VárnaiUniversity of Birmingham Verified email at bham.ac.uk Cited by 5888 |
[HTML][HTML] COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study
Background Individuals with cancer, particularly those who are receiving systemic anticancer
treatments, have been postulated to be at increased risk of mortality from COVID-19. This …
treatments, have been postulated to be at increased risk of mortality from COVID-19. This …
[HTML][HTML] COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study
…, C Usborne, C Dobeson, C Thirlwell, C Mitchell… - The Lancet …, 2020 - thelancet.com
Background Patients with cancer are purported to have poor COVID-19 outcomes. However,
cancer is a heterogeneous group of diseases, encompassing a spectrum of tumour …
cancer is a heterogeneous group of diseases, encompassing a spectrum of tumour …
Cell-cycle dynamics of chromosomal organization at single-cell resolution
… Here we scale up single-cell Hi-C 12 using flow cytometry sorting, a new library preparation
protocol and a new automation scheme, and apply this methodology to thousands of diploid …
protocol and a new automation scheme, and apply this methodology to thousands of diploid …
Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins
… In a separate experiment, we analyzed the same cells after 0 and 120 min of auxin treatment
(Fig EV2; all Hi-C libraries analyzed in this study and their properties are listed in Table EV1…
(Fig EV2; all Hi-C libraries analyzed in this study and their properties are listed in Table EV1…
[HTML][HTML] CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data
… Capture Hi-C (CHi-C) is a method for profiling chromosomal interactions involving … in CHi-C
data involves a number of statistical challenges that are not observed when using other Hi-C-…
data involves a number of statistical challenges that are not observed when using other Hi-C-…
[HTML][HTML] Severity of COVID-19 in children with cancer: report from the United Kingdom Paediatric Coronavirus Cancer Monitoring Project
…, MG McCabe, RS Phillips, CA Stiller, C Várnai… - British journal of …, 2021 - nature.com
Background Children with cancer are frequently immunocompromised. While children are
generally thought to be at less risk of severe SARS-CoV-2 infection than adults, …
generally thought to be at less risk of severe SARS-CoV-2 infection than adults, …
Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells
P Freire-Pritchett, S Schoenfelder, C Várnai… - Elife, 2017 - elifesciences.org
… , alongside the conventional Hi-C profiles additionally generated in this study … -C samples
showed an 11 to 15fold enrichment for promoter-containing interactions over conventional Hi-C…
showed an 11 to 15fold enrichment for promoter-containing interactions over conventional Hi-C…
Mortality among adults with cancer undergoing chemotherapy or immunotherapy and infected with COVID-19
Importance Large cohorts of patients with active cancers and COVID-19 infection are needed
to provide evidence of the association of recent cancer treatment and cancer type with …
to provide evidence of the association of recent cancer treatment and cancer type with …
[HTML][HTML] Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements
Zebrafish, a popular organism for studying embryonic development and for modeling human
diseases, has so far lacked a systematic functional annotation program akin to those in …
diseases, has so far lacked a systematic functional annotation program akin to those in …
[HTML][HTML] Comparison of Hi-C results using in-solution versus in-nucleus ligation
… 4C, 5C and Hi-C have emerged as standard tools to … C, we devised an alternative Hi-C
protocol with ligation in preserved nuclei rather than in solution. Here we directly compare Hi-C …
protocol with ligation in preserved nuclei rather than in solution. Here we directly compare Hi-C …