User profiles for C. Tetzlaff

Dr. Christian Tetzlaff

University Medical Center Göttingen
Verified email at med.uni-goettingen.de
Cited by 1180

[HTML][HTML] Opposing effects of neuronal activity on structural plasticity

M Fauth, C Tetzlaff - Frontiers in neuroanatomy, 2016 - frontiersin.org
The connectivity of the brain is continuously adjusted to new environmental influences by
several activity-dependent adaptive processes. The most investigated adaptive mechanism is …

[HTML][HTML] Time scales of memory, learning, and plasticity

C Tetzlaff, C Kolodziejski, I Markelic, F Wörgötter - Biological cybernetics, 2012 - Springer
After only about 10 days would the storage capacity of our nervous system be reached if we
stored every bit of input. The nervous system relies on at least two mechanisms that …

[HTML][HTML] CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing

AB Lehr, A Kumar, C Tetzlaff, T Hafting, M Fyhn… - Neuroscience & …, 2021 - Elsevier
Hippocampal region CA2 has received increased attention due to its importance in social
recognition memory. While its specific function remains to be identified, there are indications …

[HTML][HTML] Self-organized criticality in developing neuronal networks

C Tetzlaff, S Okujeni, U Egert… - PLoS computational …, 2010 - journals.plos.org
… Panel (C) shows the activity pattern that arises in our model, which at a first glance looks
similar to that in the culture. Details about the model and an analysis which support similarity of …

A Gene Cluster for Biosynthesis of the Sesquiterpenoid Antibiotic Pentalenolactone in Streptomyces avermitilis

CN Tetzlaff, Z You, DE Cane, S Takamatsu… - Biochemistry, 2006 - ACS Publications
… GC-MS was performed using a chiral 25 m × 0.25 mm hydrodex-β-6-TBDM column (Macherey-Nagel)
with a temperature ramp of 45−180 C at 2 C/min and an inlet temperature of 150 C

[HTML][HTML] Synaptic scaling in combination with many generic plasticity mechanisms stabilizes circuit connectivity

C Tetzlaff, C Kolodziejski, M Timme… - Frontiers in …, 2011 - frontiersin.org
Synaptic scaling is a slow process that modifies synapses, keeping the firing rate of neural
circuits in specific regimes. Together with other processes, such as conventional synaptic …

[HTML][HTML] Evolving artificial neural networks with feedback

S Herzog, C Tetzlaff, F Wörgötter - Neural Networks, 2020 - Elsevier
Neural networks in the brain are dominated by sometimes more than 60% feedback connections,
which most often have small synaptic weights. Different from this, little is known how to …

[HTML][HTML] Emulating dendritic computing paradigms on analog neuromorphic hardware

J Kaiser, S Billaudelle, E Müller, C Tetzlaff, J Schemmel… - Neuroscience, 2022 - Elsevier
BrainScaleS-2 is an accelerated and highly configurable neuromorphic system with physical
models of neurons and synapses. Beyond networks of spiking point neurons, it allows for …

[HTML][HTML] The formation of multi-synaptic connections by the interaction of synaptic and structural plasticity and their functional consequences

M Fauth, F Wörgötter, C Tetzlaff - PLoS computational biology, 2015 - journals.plos.org
… The term p cf contains an offset term p build and combinatorial factors, which are shaped
by properties of the neuron model via S [ v i * ] : we find that that p c f [ v i * ] takes a …

Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors

…, CS Denlinger, SK Roethke, CH Tetzlaff… - Investigational new …, 2015 - Springer
Introduction Drugs inhibiting the mammalian target of rapamycin (mTOR) are approved in
the treatment of renal cell carcinoma (RCC), but resistance inevitably emerges. Proposed …