User profiles for C. Savage-Dunn

Cathy Savage-Dunn

Queens College, CUNY
Verified email at qc.cuny.edu
Cited by 3123

[HTML][HTML] TGF-β signaling in C. elegans

TL Gumienny, C Savage-Dunn - … : The online review of C. elegans …, 2018 - ncbi.nlm.nih.gov
Transforming Growth Factor-β (TGF-β) superfamily ligands regulate many aspects of cell
identity, function, and survival in multicellular animals. Genes encoding five TGF-β family …

TGF-beta signaling.

C Savage-Dunn - WormBook, 2005 - ncbi.nlm.nih.gov
… -beta-related signals and signal transduction cassettes in C. elegans. Homology searches of
the … Thus, TGF-beta-related signaling in C. elegans proceeds via both conserved and novel …

The TGF-β family in Caenorhabditis elegans

C Savage-Dunn, RW Padgett - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
… Current studies in C. elegans continue to identify new functions for the TGF-β family in this
… pathway and the C. elegans Sma/Mab pathway. (A) The classic TGF-β signaling pathway. …

A BMP homolog acts as a dose-dependent regulator of body size and male tail patterning in Caenorhabditis elegans

…, PJ Roy, S Krishna, C Savage-Dunn… - …, 1999 - journals.biologists.com
We cloned the dbl-1 gene, a C. elegans homolog of Drosophila decapentaplegic and vertebrate
BMP genes. Loss-of-function mutations in dbl-1 cause markedly reduced body size and …

Meisosomes, folded membrane microdomains between the apical extracellular matrix and epidermis

…, B Dehapiot, C Savage-Dunn, F Richard, C Cazevieille… - Elife, 2023 - elifesciences.org
… 45C, the samples were infiltrated with gradients of HM20 resin over 9 hr, with pure resin for
18 hr at –45C and the resin was polymerised under UV for 24 hr at –45C and for 12 hr at 0C. …

The expression of TGFβ signal transducers in the hypodermis regulates body size in C. elegans

J Wang, R Tokarz, C Savage-Dunn - 2002 - journals.biologists.com
In C. elegans, a TGFβ-related signaling pathway regulates body size. Loss of function of the
signaling ligand (dbl-1),receptors (daf-4 and sma-6) or Smads (sma-2, sma-3and sma-4) …

[HTML][HTML] Transcriptional repressor and activator activities of SMA-9 contribute differentially to BMP-related signaling outputs

J Liang, L Yu, J Yin, C Savage-Dunn - Developmental biology, 2007 - Elsevier
… Notably, we demonstrate that T27F2.4, a C. elegans homolog of the mouse gene fosB, is
a downstream negative regulator of DBL-1 pathway-regulated development. Taken together, …

Caenorhabditis elegans DBL-1/BMP Regulates Lipid Accumulation via Interaction with Insulin Signaling

…, G Ranepura, DH Hall, C Savage-Dunn - G3: Genes …, 2018 - academic.oup.com
… Here we introduce DBL-1, the C. elegans homolog of bone morphogenetic protein 2/4 (…
We conclude that BMP signaling regulates lipid metabolism in C. elegans through interorgan …

The Caenorhabditis elegans schnurri homolog sma-9mediates stage- and cell type-specific responses to DBL-1 BMP-related signaling

…, R Tokarz, L Yu, SW Emmons, J Liu, C Savage-Dunn - 2003 - journals.biologists.com
… affecting body size or male sensory ray patterning (Savage-Dunn et al.,2003; Lints and
Emmons,2002). Here we report the isolation of the C. elegans shnhomolog sma-9, and provide …

BMP Signaling Determines Body Size via Transcriptional Regulation of Collagen Genes in Caenorhabditis elegans

…, M Meade, JF Clark, CA Rushlow, C Savage-Dunn - Genetics, 2018 - academic.oup.com
… Receptor-regulated Smads (R-Smads) are directly phosphorylated by the TGF-β receptors
on the C-… C. elegans strains were grown at 20 using standard methods (Brenner 1974). All …