Dealing with low pH: entry and exit of alphaviruses and flaviviruses
C Sánchez-San Martín, CY Liu, M Kielian - Trends in microbiology, 2009 - cell.com
… the two groups of viruses (Figure 2a and c ). Each protein contains an amino-terminal domain
I (… DIII has an immunoglobulin-like fold, and connects to the C-terminal stem region and TM …
I (… DIII has an immunoglobulin-like fold, and connects to the C-terminal stem region and TM …
Different rotavirus strains enter MA104 cells through different endocytic pathways: the role of clathrin-mediated endocytosis
M Gutiérrez, P Isa, C Sánchez-San Martin… - Journal of …, 2010 - Am Soc Microbiol
Rotaviruses, the single most important agents of acute severe gastroenteritis in children, are
nonenveloped viruses formed by a three-layered capsid that encloses a genome formed by …
nonenveloped viruses formed by a three-layered capsid that encloses a genome formed by …
Characterization of rotavirus cell entry
While recently we have learned much about the viral and cellular proteins involved in the
initial attachment of rotaviruses to MA104 cells, the mechanism by which these viruses reach …
initial attachment of rotaviruses to MA104 cells, the mechanism by which these viruses reach …
Differential cholesterol binding by class II fusion proteins determines membrane fusion properties
M Umashankar, C Sánchez-San Martín, M Liao… - Journal of …, 2008 - Am Soc Microbiol
… cells were infected with serial dilutions of virus for 2 h at 28C and cultured overnight (alphaviruses)
or for 2 to 4 days at 28C (flaviviruses) in medium containing 20 mM NH 4 Cl to …
or for 2 to 4 days at 28C (flaviviruses) in medium containing 20 mM NH 4 Cl to …
[HTML][HTML] Experimental Zika virus infection in the pregnant common marmoset induces spontaneous fetal loss and neurodevelopmental abnormalities
M Seferovic, C Sánchez-San Martín, SD Tardif… - Scientific reports, 2018 - nature.com
During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly
shown to cause fetal loss and congenital malformations in acutely and chronically infected …
shown to cause fetal loss and congenital malformations in acutely and chronically infected …
Characterization of human astrovirus cell entry
…, C Muñoz-Yañez, C Sánchez-San Martín… - Journal of …, 2014 - Am Soc Microbiol
Human astroviruses (HAstV) are a frequent cause of gastroenteritis in young children and
immunocompromised patients. To understand the early steps of HAstV infection in the highly …
immunocompromised patients. To understand the early steps of HAstV infection in the highly …
[HTML][HTML] Experimental Zika virus inoculation in a New World monkey model reproduces key features of the human infection
… of inactivated marmoset sera and incubated for 1 hr at 36 C, followed by inoculation and
adsorbing to a monolayer culture of Vero cells for 1 hr at 36 C. After addition of 3 mL of 1% agar …
adsorbing to a monolayer culture of Vero cells for 1 hr at 36 C. After addition of 3 mL of 1% agar …
[PDF][PDF] A stable prefusion intermediate of the alphavirus fusion protein reveals critical features of class II membrane fusion
C Sánchez-San Martín, H Sosa, M Kielian - Cell host & microbe, 2008 - cell.com
Alphaviruses infect cells via a low-pH-triggered membrane fusion reaction mediated by the
class II virus fusion protein E1, an elongated molecule with three extramembrane domains (DI…
class II virus fusion protein E1, an elongated molecule with three extramembrane domains (DI…
[HTML][HTML] Differentiation enhances Zika virus infection of neuronal brain cells
… All cells were maintained at 37 C in a humidified incubator with a 5% CO2 atmosphere. …
wells of 6-well plates, followed by incubation at 37 C for 1 hr for adsorption. After adsorption, the …
wells of 6-well plates, followed by incubation at 37 C for 1 hr for adsorption. After adsorption, the …
Metagenomic next-generation sequencing of the 2014 Ebola virus disease outbreak in the Democratic Republic of the Congo
…, G Yu, C Sanchez-San Martin… - Journal of clinical …, 2019 - Am Soc Microbiol
… Conditions for the qRT-PCR were modified as follows: 50C for 30 min and 95C for 15 min,
followed by 40 cycles of 95C for 15 s, 57C for 30 s, and 72C for 30 s, with a fluorescence …
followed by 40 cycles of 95C for 15 s, 57C for 30 s, and 72C for 30 s, with a fluorescence …