User profiles for C. Roth

Christian L Roth

Professor of Pediatrics, University of Washington, Seattle
Verified email at seattlechildrens.org
Cited by 9732

Minireview: the neuroendocrine regulation of puberty: is the time ripe for a systems biology approach?

…, A Lomniczi, C Mastronardi, S Heger, C Roth… - …, 2006 - academic.oup.com
The initiation of mammalian puberty requires an increase in pulsatile release of GnRH from
the hypothalamus. This increase is brought about by coordinated changes in transsynaptic …

The posterior reversible encephalopathy syndrome: what's certain, what's new?

C Roth, A Ferbert - Practical neurology, 2011 - pn.bmj.com
The posterior reversible encephalopathy syndrome is an increasingly recognised disorder.
Most patients have several symptoms; seizures are the most frequent, often multiple or status …

Hantavirus infection: a review and global update

Z Bi, PBH Formenty, CE Roth - The Journal of Infection in Developing …, 2008 - jidc.org
Hantaviruses have the potential to cause two different types of diseases in human: hemorrhagic
fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). HFRS, …

Pandemic potential of a strain of influenza A (H1N1): early findings

…, F Checchi, E Garcia, S Hugonnet, C Roth… - science, 2009 - science.org
A novel influenza A (H1N1) virus has spread rapidly across the globe. Judging its pandemic
potential is difficult with limited data, but nevertheless essential to inform appropriate health …

The Genome Sequence of the Malaria Mosquito Anopheles gambiae

…, M Coluzzi, A della Torre, CW Roth, C Louis… - science, 2002 - science.org
Anopheles gambiae is the principal vector of malaria, a disease that afflicts more than 500
million people and causes more than 1 million deaths each year. Tenfold shotgun sequence …

Massive migration from the steppe was a source for Indo-European languages in Europe

…, SL Pichler, R Risch, MA Rojo Guerra, C Roth… - Nature, 2015 - nature.com
… temperature from 65 C to 60 C and performed stringent washes at 55 C instead of 60 C 32 .
… UDG-treated libraries with a minimum of 3% C→T substitutions as recommended by ref. 33. …

Genome Sequence of Aedes aegypti, a Major Arbovirus Vector

…, H Quesneville, KR Reidenbach, YH Rogers, CW Roth… - Science, 2007 - science.org
We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow
fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the …

Psychiatric risk factors for adolescent suicide: a case-control study

…, G Moritz, C Allman, AMY Friend, C Roth… - Journal of the American …, 1993 - Elsevier
Objective The objective of this study was to determine the psychiatric risk factors for
adolescent suicide. Method Sixty-seven adolescent suicide victims were compared with 67 …

[HTML][HTML] A specific cholesterol binding site is established by the 2.8 Ĺ structure of the human β2-adrenergic receptor

MA Hanson, V Cherezov, MT Griffith, CB Roth… - Structure, 2008 - cell.com
The role of cholesterol in eukaryotic membrane protein function has been attributed primarily
to an influence on membrane fluidity and curvature. We present the 2.8 Ĺ resolution crystal …

Structural basis for allosteric regulation of GPCRs by sodium ions

…, P Chubukov, F Xu, V Katritch, GW Han, CB Roth… - Science, 2012 - science.org
Pharmacological responses of G protein–coupled receptors (GPCRs) can be fine-tuned by
allosteric modulators. Structural studies of such effects have been limited due to the medium …