User profiles for C. Ramakrishnan

Cartic Ramakrishnan

Vice President & Head of Applied AI @ Causaly
Verified email at genpact.digital
Cited by 2189

[HTML][HTML] Layout-aware text extraction from full-text PDF of scientific articles

C Ramakrishnan, A Patnia, E Hovy… - Source code for biology …, 2012 - Springer
Background The Portable Document Format (PDF) is the most commonly used file format for
online scientific publications. The absence of effective means to extract text from these PDF …

Neocortical excitation/inhibition balance in information processing and social dysfunction

…, JT Paz, K Stehfest, R Fudim, C Ramakrishnan… - Nature, 2011 - nature.com
… We confirmed, using c-Fos staining as a marker of activity, that in the awake state neural
activity could be increased or decreased by activation of SSFO in pyramidal and PV neurons …

Structural and molecular interrogation of intact biological systems

…, AK Denisin, S Pak, H Bernstein, C Ramakrishnan… - Nature, 2013 - nature.com
… (2) Submerge the tube in 37 C water bath in a 37 C room or incubator on the rotator. Incubate
for 3 h or until solution has polymerized. (3) In a fume hood, extract the embedded sample …

[PDF][PDF] Stereochemical criteria for polypeptide and protein chain conformations: II. Allowed conformations for a pair of peptide units

C Ramakrishnan, GN Ramachandran - Biophysical journal, 1965 - cell.com
The conformation of a polypeptide or protein chain may be specified by stating the orientations
of the two linked peptide residues at each alpha carbon atom in the chain, namely the two …

Amygdala circuitry mediating reversible and bidirectional control of anxiety

…, KR Thompson, V Gradinaru, C Ramakrishnan… - Nature, 2011 - nature.com
… We found a significantly higher proportion of c-fos-positive BLA cells in the ChR2:BLA(somata)
group (F 2,9 = 10.12, P < 0.01), relative to the ChR2:BLA–CeA or eYFP:BLA–CeA groups …

Three-dimensional intact-tissue sequencing of single-cell transcriptional states

…, S Vesuna, K Evans, C Liu, C Ramakrishnan… - Science, 2018 - science.org
INTRODUCTION Single-cell RNA sequencing has demonstrated that both stable cell types
and transient cell states can be discovered and defined by transcriptomes. In situ …

[HTML][HTML] Molecular and cellular approaches for diversifying and extending optogenetics

V Gradinaru, F Zhang, C Ramakrishnan, J Mattis… - Cell, 2010 - cell.com
Optogenetic technologies employ light to control biological processes within targeted cells
in vivo with high temporal precision. Here, we show that application of molecular trafficking …

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

…, I Goshen, DS Kim, LE Fenno, C Ramakrishnan… - Nature, 2010 - nature.com
Despite a rapidly-growing scientific and clinical brain imaging literature based on functional
magnetic resonance imaging (fMRI) using blood oxygenation level-dependent (BOLD) 1 …

Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

J Mattis, KM Tye, EA Ferenczi, C Ramakrishnan… - Nature …, 2012 - nature.com
… Although both tools showed faster off kinetics (the expected result because we performed
this experiment at 32 C rather than room temperature), the relationship seen in culture was …

Midbrain circuits for defensive behaviour

…, C Ramakrishnan, L Fenno, K Deisseroth, C Herry… - Nature, 2016 - nature.com
… Sections were incubated for 48 h in primary antibodies at 4 C followed by one overnight
incubation with secondary antibodies at 4 C. Primary antibodies used in this study were as …