Ionic liquids were initially proposed as replacements for conventional organic solvents;
however, their chemistry has developed remarkably and offers unexpected opportunities in …

… Funding for authors AR Madureira and CI Pereira was via Ph.D. fellowships,
administered by Fundação para a Ciência ea Tecnologia (SFRH/BD/18500/2004 and SFRH/BD/18000/…

This review provides an updated overview of the most important applications of supercritical
fluids in the extraction of bioactive compounds from plant matrices. The main factors …

Background In two of three phase 3 trials, pirfenidone, an oral antifibrotic therapy, reduced
disease progression, as measured by the decline in forced vital capacity (FVC) or vital …

Atrophic gastritis, intestinal metaplasia, and epithelial dysplasia of the stomach are common
and are associated with an increased risk for gastric cancer. In the absence of guidelines, …

Background: This guideline addresses the diagnosis of hypersensitivity pneumonitis (HP). It
represents a collaborative effort among the American Thoracic Society, Japanese …

Objective: To describe spirometric reference equations for healthy Brazilian adults who have
never smoked and to compare the predicted values with those derived in 1992. Methods: …

Somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by overexpressing
combinations of factors such as Oct4, Sox2, Klf4, and c-Myc. Reprogramming is slow …

Background Political, economic, and epidemiological changes in Brazil have affected health
and the health system. We used the Global Burden of Disease Study 2016 (GBD 2016) …

BACKGROUND: Percutaneous transluminal angioplasty has been used with increasing
frequency in the treatment of infrainguinal arterial occlusive disease. This meta-analysis aimed …