… (c) A schematic of methods for mapping the precise protein binding sites on RNA. PAR-CLIP
takes advantage of U → C transitions induced by UV crosslinking after 4SU incorporation. …

Background Impulsivity is considered a possible phenotype underlying the expression of
self-harm and suicidal behaviors. Yet impulsivity is a not a unitary construct and there is …

In eukaryotes, post-translational modification of histones is critical for regulation of chromatin
structure and gene expression. EZH2 is the catalytic subunit of the polycomb repressive …

Objective: Suicidal ideation and suicidal behaviour are both regarded as important risk factors
for suicide, but it is usually believed that suicidal ideation is less strongly linked to suicide …

… at 67 C for 30 min on an Eppendorf Thermomixer C with intermittent shaking as above.
Beads with captured hybrids were washed 6 times with LiCl/Urea Hybridization Buffer at 67 …

We describe the baseline coupled model configuration and simulation characteristics of
GFDL's Earth System Model Version 4.1 (ESM4.1), which builds on component and coupled …

The EZH2 histone methyltransferase is highly expressed in germinal center (GC) B cells
and targeted by somatic mutations in B cell lymphomas. Here, we find that EZH2 deletion or …

We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …

Genome‐wide scans of nucleotide variation in human subjects are providing an increasing
number of replicated associations with complex disease traits. Most of the variants detected …

Changing collective behaviour and supporting non-pharmaceutical interventions is an
important component in mitigating virus transmission during a pandemic. In a large international …