Diabetes mellitus is 1one of the most common chronic diseases in the world, with an estimated
worldwide prevalence of over 176 million in 2000. Furthermore, the prevalence of the …

… CFH, which is devoid of the endothelium-binding C-terminus, maintain regulation of plasma
levels of C3 … mutations associated with HUS are located within the C-terminal region of CFH. …

Many factors influence the long‐term outcome of kidney transplantation, which is defined
very schematically by patient death or renal dysfunction leading to graft loss. The most …

Background Atypical hemolytic–uremic syndrome is a genetic, life-threatening, chronic disease
of complement-mediated thrombotic microangiopathy. Plasma exchange or infusion may …

The 10th Banff Conference on Allograft Pathology was held in Banff, Canada from August 9
to 14, 2009. A total of 263 transplant clinicians, pathologists, surgeons, immunologists and …

Background Anti-HLA antibodies hamper successful transplantation, and activation of the
complement cascade is involved in antibody-mediated rejection. We investigated whether the …

The XIII Banff meeting, held in conjunction the Canadian Society of Transplantation in
Vancouver, Canada, reviewed the clinical impact of updates of C4d-negative antibody-mediated …

Background Cytomegalovirus (CMV) disease is a major complication of organ transplantation.
We hypothesized that prophylactic treatment with valacyclovir would reduce the risk of …

Background Hydroxyethylstarch used as a plasma-volume expander in brain-dead kidney
donors has been suggested to induce osmotic-nephrosis-like lesions. We have studied its …

… The primary end point was the proportion of patients within the targeted C … C 0 . In the group
receiving the adapted dose, a higher proportion of patients had values within the targeted C …