Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes

…, S Singh, H Han, CT Davis, B Borgeson, C Hartland… - Nature protocols, 2016 - nature.com
In morphological profiling, quantitative data are extracted from microscopy images of cells to
identify biologically relevant similarities and differences among samples based on these …

Multi-armed bandit, dynamic environments and meta-bandits

C Hartland, S Gelly, N Baskiotis, O Teytaud, M Sebag - 2006 - hal.science
This paper presents the Adapt-EvE algorithm, extending the UCBT online learning algorithm
(Auer et al. 2002) to abruptly changing environments. Adapt-EvE features an adaptive …

Nonaxisymmetric turbine end wall design: part II—experimental validation

JC Hartland, DG Gregory-Smith… - J …, 2000 - asmedigitalcollection.asme.org
… details are given by Hartland 7. Figure 5 shows the results at slot 6, −29 percent C ax . The
… These are expressed as a loss coefficient, C p 0 , defined as (upstream−local total pressure)/…

Cell Painting predicts impact of lung cancer variants

…, F Piccioni, MA Bray, CL Hartland… - Molecular biology of …, 2022 - Am Soc Cell Biol
Most variants in most genes across most organisms have an unknown impact on the function
of the corresponding gene. This gap in knowledge is especially acute in cancer, where …

Colour-causing defects and their related optoelectronic transitions in single crystal CVD diamond

…, JJP Freeth, SJ Sibley, CB Hartland… - Journal of Physics …, 2013 - iopscience.iop.org
… Then, it was heated from room temperature to 400 C or 450 C at a ramp rate of 10 C min −1
using a computer-controlled Linkam TH1500 hotstage. Light from the sample was collected …

Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation

…, VB Bradley, CM Hartland… - Cardiovascular …, 2016 - academic.oup.com
Aims In developing blood vessel networks, the overall level of vessel branching often correlates
with angiogenic sprout initiations, but in some pathological situations, increased sprout …

Change point detection and meta-bandits for online learning in dynamic environments

C Hartland, N Baskiotis, S Gelly, M Sebag… - CAp 2007: 9è …, 2007 - inria.hal.science
Motivated by realtime website optimization, this paper is about online learning in abruptly
changing environments. Two extensions of the UCBT algorithm are combined in order to …

Therapeutic effects of aerobic and resistance exercises for cancer survivors: a systematic review of meta-analyses of clinical trials

JT Fuller, MC Hartland, LT Maloney… - British journal of sports …, 2018 - bjsm.bmj.com
Objective To systematically appraise and summarise meta-analyses investigating the effect
of exercise compared with a control condition on health outcomes in cancer survivors. …

[HTML][HTML] A small molecule inhibitor of the MITF molecular pathway

…, RA Smith, J Wurst, M Weiwer, C Hartland… - Probe Reports from …, 2014 - ncbi.nlm.nih.gov
… H NMR, 13 C NMR and HRMS were used to characterize this compound and the results are
consistent with the proposed structure. UPLC purity of the material studied was 100% at 214 …

[HTML][HTML] Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway

…, F Kurreeman, EJ Rossin, G Duclos, C Hartland… - PLoS …, 2013 - journals.plos.org
… For CD40 activation, cells were incubated at 37C for 15 minutes with 64 ng/ml trimerized …
After cells were incubated at 37C for 1 hour, 10 uL (192 ng/mL) tCD40L was added to make …