Epistasis: too often neglected in complex trait studies?
Ö Carlborg, CS Haley - Nature Reviews Genetics, 2004 - nature.com
Interactions among loci or between genes and environmental factors make a substantial
contribution to variation in complex traits such as disease susceptibility. Nonetheless, many …
contribution to variation in complex traits such as disease susceptibility. Nonetheless, many …
An overview of the Odin atmospheric mission
Odin is a 250 kg class satellite built in co-operation between Sweden, Canada, France, and
Finland and launched in February 2001. It carries two instruments: a 4-band sub-millimetre …
Finland and launched in February 2001. It carries two instruments: a 4-band sub-millimetre …
Detecting epistasis in human complex traits
Genome-wide association studies (GWASs) have become the focus of the statistical analysis
of complex traits in humans, successfully shedding light on several aspects of genetic …
of complex traits in humans, successfully shedding light on several aspects of genetic …
[HTML][HTML] Genetic mechanisms of critical illness in COVID-19
, … , Cardiff, UK Lynch C. 93 Pothecary C. 93 Roche L. 93 … - Nature, 2021 - nature.com
Host-mediated lung inflammation is present 1 , and drives mortality 2 , in the critical illness
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …
A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
CS Haley, SA Knott - Heredity, 1992 - nature.com
… Their results confirm our own (this paper and Knott & Haley, 1992) in demonstrating the
biases that can be introduced when the possibility of two linked loci is ignored. …
biases that can be introduced when the possibility of two linked loci is ignored. …
Economic impact of porcine reproductive and respiratory syndrome virus on US pork producers
…, P Yeske, CL Mowrer, C Haley - Iowa State …, 2012 - iastatedigitalpress.com
… Derald Holtkamp, Iowa State University; James Kliebenstein, Iowa State University; Jeff
Zimmerman, Iowa State University; Eric Neumann, Massey University, Hans Rotto …
Zimmerman, Iowa State University; Eric Neumann, Massey University, Hans Rotto …
A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig
…, C Collette, L Moreau, AL Archibald, CS Haley… - Nature, 2003 - nature.com
Most traits and disorders have a multifactorial background indicating that they are controlled
by environmental factors as well as an unknown number of quantitative trait loci (QTLs) 1 , 2 …
by environmental factors as well as an unknown number of quantitative trait loci (QTLs) 1 , 2 …
Genetic mapping of quantitative trait loci for growth and fatness in pigs
L Andersson, CS Haley, H Ellegren, SA Knott… - Science, 1994 - science.org
The European wild boar was crossed with the domesticated Large White pig to genetically
dissect phenotypic differences between these populations for growth and fat deposition. The …
dissect phenotypic differences between these populations for growth and fat deposition. The …
Mapping quantitative trait loci in crosses between outbred lines using least squares.
CS Haley, SA Knott, JM Elsen - Genetics, 1994 - academic.oup.com
… and C are used (these correspond to markers A, B and C for … for crosses between inbred
lines (HALEY and horn 1992), a … a time [Table 5 and &om and HALEY (1992b)l. The prediction …
lines (HALEY and horn 1992), a … a time [Table 5 and &om and HALEY (1992b)l. The prediction …
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
Circulating proteins are vital in human health and disease and are frequently used as
biomarkers for clinical decision-making or as targets for pharmacological intervention. Here, we …
biomarkers for clinical decision-making or as targets for pharmacological intervention. Here, we …