User profiles for C. Gruget

Clemence Gruget

MIT
Verified email at mit.edu
Cited by 164

[HTML][HTML] Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension

…, M Bergé, T Perry, AL Soulet, C Gruget… - Nature …, 2017 - nature.com
… Pre-competent wild type cultures grown at 37 C in C+Y … at 37 C to induce competence. DNA
(concentrations indicated on figures) was then added followed by 20 min incubation at 30 C. …

[HTML][HTML] Synaptotagmin-1 membrane binding is driven by the C2B domain and assisted cooperatively by the C2A domain

C Gruget, O Bello, J Coleman, SS Krishnakumar… - Scientific Reports, 2020 - nature.com
… For each run we measured the distance shift ΔD occurring during the contact time t c that
corresponds to the variation of the distance between the last point of approach and the first …

[HTML][HTML] Efficacy and safety of agomelatine (10 or 25 mg/day) in non-depressed out-patients with generalized anxiety disorder: a 12-week, double-blind, placebo …

…, L Vavrusova, O Chaban, C Gruget… - European …, 2017 - Elsevier
Agomelatine is efficacious in reducing symptoms and preventing relapse in placebo-controlled
trials in generalised anxiety disorder (GAD). Nevertheless, fixed dose studies of …

Better sexual acceptability of agomelatine (25 and 50 mg) compared to escitalopram (20 mg) in healthy volunteers. A 9-week, placebo-controlled study using the …

…, C Gabriel, C Gruget, C Klinge… - Journal of …, 2015 - journals.sagepub.com
The present double-blind, placebo-controlled study evaluates the effects of agomelatine
and the selective serotonin reuptake inhibitor escitalopram on sexual dysfunction in healthy …

Fission yeast kinesin-8 controls chromosome congression independently of oscillations

…, G Gay, C Reyes, T Gauthier, C Gruget… - Journal of Cell …, 2015 - journals.biologists.com
… Cells were blocked in G2 at the restrictive temperature, released into mitosis at 25C and the
Klp5–GFP signal was captured at a high frame rate (frames were taken every 2 s). (C) Klp5–…

[HTML][HTML] On-chip quantitative measurement of mechanical stresses during cell migration with emulsion droplets

D Molino, S Quignard, C Gruget, F Pincet, Y Chen… - Scientific Reports, 2016 - nature.com
… R C decreases until it reaches the radius of the pipette R P . Up to that critical aspiration ΔP
c , … As soon as ΔP is larger than ΔP c , R C becomes smaller than R P , which results in the …

Rearrangements under confinement lead to increased binding energy of Synaptotagmin‐1 with anionic membranes in Mg2+ and Ca2+

C Gruget, J Coleman, O Bello, SS Krishnakumar… - FEBS …, 2018 - Wiley Online Library
… In the standard procedure, we apply a 1 h contact time (t c = 1 h) between the end of the
approach and the beginning of the separation, with shorter t c in specific cases. The surfaces are …

[HTML][HTML] Randomized Efficacy and Safety Trial with Oral S 44819 after Recent ischemic cerebral Event (RESTORE BRAIN study): a placebo controlled phase II study

…, U Marx, F Picarel-Blanchot, A Sors, C Gruget… - Trials, 2020 - Springer
… For suicidal ideation score from the C-SSRS, the number and percentage of patients is
assessed considering their maximum suicidal ideation score during treatment. Suicidal ideation …

[PDF][PDF] Synaptotagmin Interactions with Membranes: Measuring the Force of Calcium Triggering of Neurotransmission

C Gruget, J Coleman, S Krishankumar, JE Rothman… - Biophysical …, 2017 - cell.com
34a Sunday, February 12, 2017 proteins assembly, but the previous experiments did not
include Syt1. In our set up, both surfaces are coated with a lipid bilayer. One of them mimics the …

Droplets bumpers as mechanical sensors for cell migration under confinement

D Molino, S Quignard, C Gruget, F Pincet, Y Chen… - bioRxiv, 2016 - biorxiv.org
… R C decreases until it reaches the radius of the pipette R P . Up to that critical aspiration ΔP
c , … As soon as ΔP is larger than ΔP c , R C becomes smaller than R P , which results in the …