[HTML][HTML] Unicycler: resolving bacterial genome assemblies from short and long sequencing reads
The Illumina DNA sequencing platform generates accurate but short reads, which can be used
to produce accurate but fragmented genome assemblies. Pacific Biosciences and Oxford …
to produce accurate but fragmented genome assemblies. Pacific Biosciences and Oxford …
Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health
… Analysis of G+C content diversity and taxonomy indicated the K. pneumoniae accessory
genes likely were acquired from a wide range of bacterial taxa including Enterobacteriaceae, …
genes likely were acquired from a wide range of bacterial taxa including Enterobacteriaceae, …
Genomics of vancomycin-resistant Enterococcus faecium
Vancomycin-resistant Enterococcus faecium (VREfm) is a globally significant public health
threat and was listed on the World Health Organization’s 2017 list of high-priority pathogens …
threat and was listed on the World Health Organization’s 2017 list of high-priority pathogens …
Completing bacterial genome assemblies with multiplex MinION sequencing
… Clinical isolates were grown overnight at 37 C on LB agar plates, then single colonies were
picked for overnight culture at 37 C in LB. Bacterial cell pellets from 3.0 ml LB culture were …
picked for overnight culture at 37 C in LB. Bacterial cell pellets from 3.0 ml LB culture were …
Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients
… Gorrie … (C), Midpoint rooted species tree for K. pneumoniae sensu stricto isolates. … (C),
Midpoint rooted species tree for K. pneumoniae sensu stricto isolates. …
Midpoint rooted species tree for K. pneumoniae sensu stricto isolates. …
[HTML][HTML] Identification of Klebsiella capsule synthesis loci from whole genome data
Klebsiella pneumoniae is a growing cause of healthcare-associated infections for which
multi-drug resistance is a concern. Its polysaccharide capsule is a major virulence determinant …
multi-drug resistance is a concern. Its polysaccharide capsule is a major virulence determinant …
[HTML][HTML] Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen
Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases (…
which are increasingly complicated by the presence of extended-spectrum beta-lactamases (…
Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations
… (a) Gene structure for core modules, which are shown in b and c as coloured blocks:
yersiniabactin synthesis locus ybt (dark grey, labelled with the most commonly associated ybt …
yersiniabactin synthesis locus ybt (dark grey, labelled with the most commonly associated ybt …
[HTML][HTML] Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae
Klebsiella pneumoniae has emerged as an important cause of two distinct public health
threats: multi-drug resistant (MDR) healthcare-associated infections and drug susceptible …
threats: multi-drug resistant (MDR) healthcare-associated infections and drug susceptible …
[HTML][HTML] An ISO-certified genomics workflow for identification and surveillance of antimicrobial resistance
…, SA Ballard, A Gonҫalves da Silva, CL Gorrie… - Nature …, 2023 - nature.com
Realising the promise of genomics to revolutionise identification and surveillance of
antimicrobial resistance (AMR) has been a long-standing challenge in clinical and public health …
antimicrobial resistance (AMR) has been a long-standing challenge in clinical and public health …