User profiles for C. Douville

Christopher Douville

Johns Hopkins University
Verified email at jhmi.edu
Cited by 5969

Practice standards for transcranial Doppler (TCD) ultrasound. Part II. Clinical indications and expected outcomes

…, CR Levy, LKS Wong, C Douville… - Journal of …, 2012 - Wiley Online Library
INTRODUCTION Transcranial Doppler (TCD) is a physiological ultrasound test with established
safety and efficacy. Although imaging devices may be used to depict intracranial flow …

Detection and localization of surgically resectable cancers with a multi-analyte blood test

…, Y Wang, C Thoburn, B Afsari, L Danilova, C Douville… - Science, 2018 - science.org
… We are grateful to C. Blair and K. Judge for expert technical and administrative assistance. …
We are grateful to C. Blair and K. Judge for expert technical and administrative assistance. …

Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention

…, HJ Hwang, K Lahouel, JD Cohen, C Douville… - Science, 2020 - science.org
INTRODUCTION The goal of earlier cancer detection is to identify the disease at a stage
when it can be effectively treated, thereby offering the patient a better chance of long-term …

A combination of molecular markers and clinical features improve the classification of pancreatic cysts

…, CL Wolfgang, T Tomita, N Niknafs, C Douville… - Gastroenterology, 2015 - Elsevier
Background & Aims The management of pancreatic cysts poses challenges to both patients
and their physicians. We investigated whether a combination of molecular markers and …

[HTML][HTML] Identifying Mendelian disease genes with the variant effect scoring tool

H Carter, C Douville, PD Stenson, DN Cooper… - BMC genomics, 2013 - Springer
… (C). The color bar for SIFT is reversed since a low SIFT score corresponds to positive
class prediction. ROC AUC is 0.92, 0.85, 0.84 for VEST, PolyPhen2 and SIFT respectively. …

Whole genome sequencing defines the genetic heterogeneity of familial pancreatic cancer

…, KG Chaffee, YC Chen, ML Cote, EJ Childs, C Douville… - Cancer discovery, 2016 - AACR
Pancreatic cancer is projected to become the second leading cause of cancer-related death
in the United States by 2020. A familial aggregation of pancreatic cancer has been …

Cerebral autoregulation following minor head injury

…, GA Grant, AM Avellino, S Ghatan, CM Douville… - Journal of …, 1997 - thejns.org
✓ The purpose of this study was to determine whether patients with minor head injury experience
impairments in cerebral autoregulation. Twenty-nine patients with minor head injuries …

Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing

…, BH Yun, M Moriya, N Niknafs, C Douville… - Science translational …, 2013 - science.org
… We also observed a preference for a C or T in the base preceding the mutated A residue,
and a preference for G at the following base in both synonymous and nonsynonymous A>T …

Practice standards for transcranial Doppler ultrasound: part I—test performance

…, MA Sloan, LKS Wong, C Douville… - Journal of …, 2007 - Wiley Online Library
Indications for the clinical use of transcranial Doppler (TCD) continue to expand while scanning
protocols and quality of reporting vary between institutions. Based on literature analysis …

CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods

…, VB Guthrie, R Bhattacharya, YC Chen, C Douville… - Genome …, 2024 - cris.unibo.it
Background: The Critical Assessment of Genome Interpretation (CAGI) aims to advance the
state-of-the-art for computational prediction of genetic variant impact, particularly where …